Motoki Sawamura

Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure.

Y. Hari, S. Obika, H. Aoyama, 2016, Organic & biomolecular chemistry.

Synthesis, duplex-forming ability, enzymatic stability, and in vitro antisense potency of oligonucleotides including 2'-C,4'-C-ethyleneoxy-bridged thymidine derivatives.

Y. Hari, S. Obika, Tsuyoshi Yamamoto, 2017, Organic & biomolecular chemistry.

Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.

Y. Hari, S. Obika, Tsuyoshi Yamamoto, 2017, The Journal of organic chemistry.

Serial incorporation of a monovalent GalNAc phosphoramidite unit into hepatocyte-targeting antisense oligonucleotides.

S. Obika, M. Harada‐Shiba, Tsuyoshi Yamamoto, 2016, Bioorganic & medicinal chemistry.

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides.

S. Obika, M. Harada‐Shiba, Shunsuke Wada, 2016, Journal of Controlled Release.

Effect of modular conjugation strategy for N-acetylgalactosamine-targeted antisense oligonucleotides

S. Obika, M. Harada‐Shiba, Tsuyoshi Yamamoto, 2020, Nucleosides, nucleotides & nucleic acids.

Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure.

Y. Hari, S. Obika, H. Aoyama, 2016, Organic & biomolecular chemistry.