J. Zephyr

发表

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.

C. Schiffer, E. Nalivaika, Akbar Ali, 2021, Chemical reviews.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.

C. Schiffer, Akbar Ali, Adam K. Hedger, 2022, Journal of molecular biology.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

C. Schiffer, E. Chan, Akbar Ali, 2021, bioRxiv.

Viral proteases: Structure, mechanism and inhibition

C. Schiffer, Nese Kurt Yilmaz, J. Zephyr, 2021, The Enzymes.

Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.

C. Schiffer, C. Petropoulos, Wei Huang, 2021, Journal of medicinal chemistry.

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

C. Schiffer, Akbar Ali, Adam K. Hedger, 2020, mBio.

Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.

Wei Huang, Akbar Ali, Celia A Schiffer, 2017, Journal of medicinal chemistry.

Can Prophylactic Epidural Blood Patch Reduce the Incidence and Severity of Postpartum Dural Puncture Headache in Obstetrics

J. Rovner, Shaul Cohen, R. Hamer, 1998 .

FruitFire: a luciferase based on a fruit fly metabolic enzyme

C. Schiffer, M. Bohn, S. Miller, 2023, bioRxiv.

Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease.

C. Schiffer, E. Nalivaika, Akbar Ali, 2022, Bioorganic chemistry.