Indrawan J. McAlpine

发表

Structural modifications of a 3-methoxy-2-aminopyridine compound to reduce potential for mutagenicity and time-dependent drug-drug interaction.

D. Bouzida, M. Pairish, S. Yamazaki, 2012, Bioorganic & medicinal chemistry letters.

Improved cyclization conditions to prepare 6-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]pyrazines using catalytic Ag(I) and Au(III) salts

N. Sach, M. Tran-Dube, S. Ninkovic, 2015 .

Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry.

M. Tran-Dube, J. Warmus, M. Collins, 2015, The Journal of organic chemistry.

Multifaceted Substrate-Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds.

P. Liu, Peng Liu, K. Engle, 2020, ACS catalysis.

Copper-Catalyzed Chan-Lam Cyclopropylation of Phenols and Azaheterocycles.

M. Tran-Dube, Fen Wang, K. Engle, 2018, The Journal of organic chemistry.

Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

M. Tran-Dube, Peng Liu, K. Engle, 2020, Nature Communications.

Studies on the regioselective nucleophilic aromatic substitution (S(N)Ar) reaction of 2-substituted 3,5-dichloropyrazines.

Fen Wang, S. Scales, Q. Hu, 2013, Organic letters.

A two-step, one-pot procedure using acid chlorides and propargyl amines to form tri-substituted oxazoles via gold-catalyzed cyclization

Indrawan J. McAlpine, Sarah Johnson, Tran-Dube Michelle Bich, 2013 .

A simple and convenient two-step, one-pot synthesis of hetero-imidazoles from nitroaminoaryls catalyzed by Ytterbium triflate

Fen Wang, S. Ninkovic, S. Scales, 2013 .

A Two‐Step, One‐Pot Procedure Using Acid Chlorides and Propargyl Amines to Form Tri‐Substituted Oxazoles via Gold‐Catalyzed Cyclization.

Indrawan J. McAlpine, Sarah Johnson, Tran-Dube Michelle Bich, 2013 .

Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity.

M. Tran-Dube, P. Liu, Peng Liu, 2019, ACS catalysis.

Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.

P. Kung, S. Yamazaki, M. Edwards, 2016, Journal of medicinal chemistry.

Design and Synthesis of Pyridone-Containing 3 , 4-Dihydroisoquinoline-1 ( 2 H ) ‐ ones as a Novel Class of Enhancer of Zeste Homolog 2 ( EZH 2 ) Inhibitors

P. Kung, S. Yamazaki, M. Edwards, 2016 .

SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

M. Tran-Dube, M. McTigue, S. Yamazaki, 2021, Molecular Cancer Therapeutics.

Discovery of pyrroloaminopyrazoles as novel PAK inhibitors.

D. Bouzida, J. Christensen, R. Kania, 2012, Journal of medicinal chemistry.

Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.

Shuyan Lu, B. Jessen, L. Marroquin, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Palladium(ii)-catalyzed γ-selective hydroarylation of alkenyl carbonyl compounds with arylboronic acids† †Electronic supplementary information (ESI) available. CCDC 1835959. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc03081b

Fen Wang, K. Engle, G. Gallego, 2018, Chemical science.

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.

Gareth J Waldron, R. Grimley, M. Andrews, 2018, Journal of medicinal chemistry.

Correction to Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.

P. Kung, S. Yamazaki, M. Edwards, 2016, Journal of Medicinal Chemistry.

AG-024322 is a multi-targeted CDK inhibitor with potent antitumor activity in vivo

Gennady M Verkhivker, D. Knighton, C. Lewis, 2005 .

AG-024322 is a potent and selective multi-targeted CDK inhibitor with broad spectrum anti-proliferative activity

Gennady M Verkhivker, D. Knighton, C. Lewis, 2005 .

Stereoselective synthesis of a tricyclic guanidinium model of cylindrospermopsin

R. W. Armstrong, Indrawan J. McAlpine, 2000 .

Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors.

R. Grimley, J. Bilsland, J. Cui, 2019, Journal of medicinal chemistry.

Synthetic Approaches to the New Drugs Approved During 2021.

C. J. O’Donnell, C. Leverett, S. Berritt, 2023, Journal of medicinal chemistry.

Rhodium(III)-Catalyzed C-H Activation: Ligand-Controlled Regioselective Synthesis of 4-Methyl-Substituted Dihydroisoquinolones.

N. Sach, M. Tran-Dube, M. Collins, 2019, Organic letters.