Alex K. Shalek

发表

Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices

David A. Weitz, Sanjay M. Prakadan, Alex K. Shalek, 2017, Nature Reviews Genetics.

Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

Alex Arenas, Mika Gustafsson, Mattias Magnusson, 2020, Genome Medicine.

Systematic comparative analysis of single cell RNA-sequencing methods

Orit Rozenblatt-Rosen, Aviv Regev, Boaz Barak, 2019, bioRxiv.

Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

Aviv Regev, Nir Hacohen, Alex K. Shalek, 2020, Nature Biotechnology.

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Masahiro Yoshida, Fabian J. Theis, Oliver Eickelberg, 2020, Nature Medicine.

Allergic inflammatory memory in human respiratory epithelial progenitor cells

Alex K. Shalek, Joshua A. Boyce, Travis K. Hughes, 2018, Nature.

Single-cell analyses to tailor treatments

Mikael Benson, Alex K. Shalek, A. Shalek, 2017, Science Translational Medicine.

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

Paul C. Blainey, Alex K. Shalek, Scott R. Manalis, 2016, Nature Communications.

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

Aviv Regev, Alex K. Shalek, Rahul Satija, 2015, Cell.

Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

Aviv Regev, Kristian Cibulskis, Todd R. Golub, 2014, Nature Biotechnology.

Computational Methods for Single-Cell RNA Sequencing

Bonnie Berger, Brian Hie, Alex K. Shalek, 2020 .

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

Simon Kasif, Miguel N. Rivera, Aviv Regev, 2014, Cell.

Deconstructing transcriptional heterogeneity in pluripotent stem cells

Aviv Regev, George Q. Daley, James J. Collins, 2014, Nature.

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

Jacob T. Robinson, Aviv Regev, Irit Gat-Viks, 2011, Cell.

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration

Jose Davila-Velderrain, Shahin Mohammadi, Manolis Kellis, 2019, Nature Communications.

SARS-CoV-2 Receptor ACE2 is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Enriched in Specific Cell Subsets Across Tissues

Fabian J Theis, Alison Yu, Alex K. Shalek, 2020, SSRN Electronic Journal.

Heterogeneity in immune responses: from populations to single cells.

Alex K. Shalek, Rahul Satija, A. Shalek, 2014, Trends in immunology.

MAST: A flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA-seq data

Greg Finak, Raphael Gottardo, Peter S. Linsley, 2015 .

Rewiring of the cellular and inter-cellular landscape of the human colon during ulcerative colitis

Aviv Regev, Hailiang Huang, Ashwin N. Ananthakrishnan, 2018 .

Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia

Jacob T. Robinson, Aviv Regev, Nir Yosef, 2012, Nano letters.

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

Mika Gustafsson, Mikael Benson, Alex K. Shalek, 2019, Genome Medicine.