I. Lyothier

发表

Total synthesis of (+)-discodermolide: an improved endgame exploiting a Still-Gennari-type olefination with a C1-C8 beta-ketophosphonate fragment.

I. Paterson, I. Lyothier, 2004, Organic letters.

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration.

U. Schopfer, S. Bevan, R. Portmann, 2007, Journal of medicinal chemistry.

Iridium-catalyzed enantioselective synthesis of allylic alcohols: silanolates as hydroxide equivalents.

E. Carreira, Christian Defieber, I. Lyothier, 2006, Angewandte Chemie.

Development of a third-generation total synthesis of (+)-discodermolide: an expedient Still-Gennari-type fragment coupling utilizing an advanced beta-ketophosphonate.

I. Paterson, I. Lyothier, 2005, The Journal of organic chemistry.

Syntheses of disaccharide- and nucleoside-substituted cyclopentadienyl and indenyl ligands

R. Laı̈, I. Lyothier, Jean-Francois Berthome, 2003 .

The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.

Jens Meiler, Ian Paterson, Karel Kubicek, 2006, Angewandte Chemie.

Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 5: Linkage of Fragments C1-6 and C7-24 and Finale

Ian Paterson, T. Ramsey, I. Paterson, 2004 .

A second-generation total synthesis of (+)-discodermolide: the development of a practical route using solely substrate-based stereocontrol.

Ian Paterson, Jeremy P. Scott, Ó. Delgado, 2005, The Journal of organic chemistry.

1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.

Jeremy P. Scott, Ó. Delgado, I. Paterson, 2003, Organic letters.

Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.

P. McIntyre, S. Bevan, A. Dyson, 2006, Journal of medicinal chemistry.