D. Shapiro

发表

Targeting multidrug-resistant ovarian cancer through estrogen receptor α dependent ATP depletion caused by hyperactivation of the unfolded protein response

E. Nelson, P. Hergenrother, Xiaobin Zheng, 2014, Oncotarget.

An estrogen-inducible protein binds specifically to a sequence in the 3' untranslated region of estrogen-stabilized vitellogenin mRNA

R. Dodson, D. Shapiro, D. J. Shapiro, 1994, Molecular and cellular biology.

Ribosome loading, but not protein synthesis, is required for estrogen stabilization of Xenopus laevis vitellogenin mRNA.

J. Blume, D. Shapiro, 1989, Nucleic acids research.

Fine structure of the cyclic rhythm of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Differential effects of cholesterol feeding and fasting.

V. Rodwell, D. Shapiro, 1972, Biochemistry.

A histone deacetylase inhibitor potentiates estrogen receptor activation of a stably integrated vitellogenin promoter in HepG2 cells.

C. Mao, D. Shapiro, 2000, Endocrinology.

8-Alkylthio-6-thio-substituted theophylline analogues as selective noncompetitive progesterone receptor antagonists

E. Wilson, S. Nordeen, D. J. Shapiro, 2012, Steroids.

Estradiol and estrogen receptor-dependent stabilization of a minivitellogenin mRNA lacking 5,100 nucleotides of coding sequence

D. Nielsen, D. Shapiro, D. J. Shapiro, 1990, Molecular and cellular biology.

A middle-affinity estrogen-specific binding protein in livers of vitellogenic and nonvitellogenic Xenopus laevis.

M. Hayward, D. Shapiro, 1981, Developmental biology.

Human estrogen receptor bound to an estrogen response element bends DNA.

G. Greene, A. Nardulli, D. Shapiro, 1993, Molecular endocrinology.

3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells.

S. Singer, M. Barton, G. Keller, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Coordinate estrogen induction of vitellogenin and a small serum protein mRNA in Xenopus laevis liver

M. Barton, M. Hayward, D. Shapiro, 1985, Molecular and Cellular Endocrinology.

Estrogen Receptor-KRAB Chimeras Are Potent Ligand-dependent Repressors of Estrogen-regulated Gene Expression*

B. Katzenellenbogen, G. de Haan, C. Mao, 2000, The Journal of Biological Chemistry.

Two functional forms of the Xenopus laevis estrogen receptor translated from a single mRNA species.

F. Claret, R. Wittek, S. Chapel, 1994, The Journal of biological chemistry.

Powerful dominant negative mutants of the human estrogen receptor.

B. Katzenellenbogen, Y. Zhuang, B. Ince, 1993, The Journal of biological chemistry.

Evaluation of a Luciferase-Based Reporter Assay as a Screen for Inhibitors of Estrogen-ERα-Induced Proliferation of Breast Cancer Cells

C. Mao, D. J. Shapiro, N. Andruska, 2012, Journal of biomolecular screening.

Interplay between Estrogen Response Element Sequence and Ligands Controls in Vivo Binding of Estrogen Receptor to Regulated Genes*

A. Krieg, Bonnie S Ahn, S. Krieg, 2004, Journal of Biological Chemistry.

Regulation of Xenopus laevis estrogen receptor gene expression is mediated by an estrogen response element in the protein coding region.

J. Kim, J. Lee, D. Shapiro, 1995, DNA and cell biology.

Small Molecule Inhibitors as Probes for Estrogen and Androgen Receptor Action*

C. Mao, D. J. Shapiro, M. Cherian, 2010, The Journal of Biological Chemistry.

Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation

M. Brock, D. Shapiro, 1983, Cell.

A high-efficiency HeLa cell nuclear transcription extract.

P. Sharp, D. J. Shapiro, D J Shapiro, 1988, DNA.

Thin-layer chromatographic assay for HMG-CoA reductase and mevalonic acid.

V. Rodwell, R. L. Imblum, D. Shapiro, 1969, Analytical biochemistry.

Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis.

D. J. Shapiro, V. Rodwell, D. Shapiro, 1971, The Journal of biological chemistry.

The immune system and inflammation in breast cancer

Xinguo Jiang, D. Shapiro, 2014, Molecular and Cellular Endocrinology.

Regulation of rat liver cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by methoxypolyoxyethylated cholesterol.

D. J. Shapiro, G. Martin, D. Shapiro, 1985, Biochimica et biophysica acta.

CHAPTER 5 – Messenger RNA Stabilization and Gene Transcription in the Estrogen Induction of Vitellogenin mRNA

D. J. Shapiro, M. Brock, D. Shapiro, 1985 .

Induction of estrogen receptor and reversal of the nuclear/cytoplasmic receptor ratio during vitellogenin synthesis and withdrawal in Xenopus laevis.

M. Hayward, T. Mitchell, D. Shapiro, 1980, The Journal of biological chemistry.

Rapid accumulation of vitellogenin messenger RNA during secondary estrogen stimulation of Xenopus laevis.

H. J. Baker, D. Shapiro, 1978, The Journal of biological chemistry.

Kinetics of estrogen induction of Xenopus laevis vitellogenin messenger RNA as measured by hybridization to complementary DNA.

D. J. Shapiro, H. J. Baker, D. Shapiro, 1977, The Journal of biological chemistry.

T. Chang, D. Shapiro, 1990, The Journal of biological chemistry.

Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells.

D. Kranz, D. J. Shapiro, B. Orr, 2006, Endocrinology.

Insights into hormonal control of messenger RNA stability.

D. Nielsen, D. Shapiro, D. J. Shapiro, 1990, Molecular endocrinology.

Isolation of hen oviduct ovalbumin and rat live albumin polysomes by indirect immunoprecipitation.

J. Taylor, R. Schimke, G. McKnight, 1974, The Journal of biological chemistry.

DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element

K. Horwitz, L. Freedman, A. Nardulli, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts.

R. Schimke, J. Nordstrom, D. J. Shapiro, 1974, Biochimica et biophysica acta.

Diurnal variation and cholesterol regulation of hepatic HMG-CoA reductase activity.

V. Rodwell, D. Shapiro, David J. Shapiro, 1969, Biochemical and biophysical research communications.

Estrogen regulates the absolute rate of transcription of the Xenopus laevis vitellogenin genes.

D. J. Shapiro, M. Brock, D. Shapiro, 1983, The Journal of biological chemistry.

A Functional Serine 118 Phosphorylation Site in Estrogen Receptor-α Is Required for Down-Regulation of Gene Expression by 17β-Estradiol and 4-Hydroxytamoxifen

Jingwei Cheng, Chen Zhang, D. Shapiro, 2007 .

Estrogen regulation of gene transcription and mRNA stability.

J. Blume, M. Barton, D. Lew, 1989, Recent progress in hormone research.

Posttranscriptional Suppression of Proto-Oncogene c-fms Expression by Vigilin in Breast Cancer

S. Chambers, I. Menzl, X. Yi, 2010, Molecular and Cellular Biology.

Prebending the estrogen response element destabilizes binding of the estrogen receptor DNA binding domain

G. de Haan, A. Nardulli, J. Kim, 1997, Molecular and cellular biology.

NEW INSIGHTS INTO A COMPLEX HOST-PATHOGEN INTERACTION: MECHANISMS OF HELICOBACTER PYLORI ACTIVATION OF NF-B BY ACACIA CHRISTINE LAMB DISSERTATION Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Biochemistry

Lin-Feng Chen, D. J. Shapiro, Y. H. Tsang, 2012 .

Regulation of pathways of mRNA destabilization and stabilization.

R. Dodson, D. Shapiro, 2002, Progress in nucleic acid research and molecular biology.

Purified estrogen receptor DNA binding domain expressed in Escherichia coli activates transcription of an estrogen-responsive promoter in cultured cells.

A. Nardulli, D. Lew, L. Erijman, 1991, The Journal of biological chemistry.

The role of estrogen response elements in expression of the Xenopus laevis vitellogenin B1 gene.

A. Nardulli, D. Lew, T. Chang, 1992, Molecular endocrinology.

A highly sensitive, mixed-phase assay for chloramphenicol acetyltransferase activity in transfected cells.

D. J. Shapiro, D. Nielsen, T. Chang, 1989, Analytical biochemistry.

Estrogen induces transcription of the Xenopus laevis serum retinol-binding protein gene.

M. Barton, D. Mckearin, M. J. Keller, 1987, The Journal of biological chemistry.

The Xenopus laevis estrogen receptor: sequence homology with human and avian receptors and identification of multiple estrogen receptor messenger ribonucleic acids.

I. Weiler, D. Lew, D. Shapiro, 1987, Molecular endocrinology.

27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression.

Joy J. Chen, Liqian Ma, Lawrence Wang, 2020, Cancer letters.

Estrogen Receptor-dependent and Estrogen Receptor-independent Pathways for Tamoxifen and 4-Hydroxytamoxifen-induced Programmed Cell Death*

D. Shapiro, Maria Obrero, David V Yu, 2002, The Journal of Biological Chemistry.

RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis.

K. Goolsby, D. Shapiro, 2003, Nucleic acids research.

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.

B. Katzenellenbogen, J. Katzenellenbogen, K. Nettles, 2017, Cancer research.

Persistent estrogen induction of hepatic Xenopus laevis serum retinol binding protein mRNA.

D. Mckearin, D. Shapiro, 1988, The Journal of biological chemistry.

CHAPTER 8 – Nucleic Acid Probes and Analysis of Hormone Action in Oviduct

R. Schimke, G. McKnight, D. Shapiro, 1975 .

Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells.

Y. Ling, D. J. Shapiro, Jianwei Xie, 2008, Endocrinology.

RNA gel shift assays for analysis of hormone control of mRNA stability.

C. Mao, R. Dodson, K. Goolsby, 2003, Methods in enzymology.

DNA bending between upstream activator sequences increases transcriptional synergy.

G. de Haan, D J Shapiro, J Kim, 1996, Biochemical and biophysical research communications.

Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending

A. Nardulli, D. Shapiro, D. J. Shapiro, 1992, Molecular and cellular biology.

Improved methods for the assay and activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

D. J. Shapiro, B. W. Philipp, D. Shapiro, 1979, Journal of lipid research.

Immunochemical isolation and characterization of ovalbumin messenger ribonucleic acid.

R. Schimke, D. Shapiro, 1975, The Journal of biological chemistry.

Vigilin, a Ubiquitous Protein with 14 K Homology Domains, Is the Estrogen-inducible Vitellogenin mRNA 3′-Untranslated Region-binding Protein*

R. Dodson, D. Shapiro, 1997, The Journal of Biological Chemistry.

Modulators of Inflammation Use Nuclear Factor-κB and Activator Protein-1 Sites to Induce the Caspase-1 and Granzyme B Inhibitor, Proteinase Inhibitor 9*

Padmamalini Kannan-Thulasiraman, D. Shapiro, 2002, The Journal of Biological Chemistry.

Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations.

B. Park, Liqun Yu, Rui Huang, 2019, Cancer letters.

Src couples estrogen receptor to the anticipatory unfolded protein response and regulates cancer cell fate under stress.

Liqun Yu, J. Kim, Lawrence Wang, 2020, Biochimica et biophysica acta. Molecular cell research.

A New Role for Estrogen Receptor α in Cell Proliferation and Cancer: Activating the Anticipatory Unfolded Protein Response

Mara R. Livezey, J. Kim, D. Shapiro, 2018, Front. Endocrinol..

Dimerizing the Estrogen Receptor DNA Binding Domain Enhances Binding to Estrogen Response Elements*

D. J. Shapiro, M. A. Kuntz, D. Shapiro, 1997, The Journal of Biological Chemistry.

Analysis of Mechanisms That Determine Dominant Negative Estrogen Receptor Effectiveness (*)

B. Katzenellenbogen, D. Schodin, Y. Zhuang, 1995, The Journal of Biological Chemistry.

In Vitro Genetic Analysis of the RNA Binding Site of Vigilin, a Multi-KH-Domain Protein

R. Dodson, H. Kanamori, D. Shapiro, 1998, Molecular and Cellular Biology.

Analysis of RNA-protein interactions by a microplate-based fluorescence anisotropy assay.

C. Mao, J. Ross, R. Dodson, 2006, Analytical biochemistry.

Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3'-untranslated region by the mRNA endonuclease polysomal ribonuclease 1.

M. Nagel, R. Dodson, Daniel R Schoenberg, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Tissue distribution, hormone regulation and evidence for a human homologue of the estrogen-inducible Xenopus laevis vitellogenin mRNA binding protein

D. J. Shapiro, R. Dodson, M. Acena, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Regulation of messenger RNA stability in eukaryotic cells

D. Nielsen, D. Shapiro, Jack E. Blume, 1987, BioEssays : news and reviews in molecular, cellular and developmental biology.

Preparation of capped RNA transcripts using T7 RNA polymerase.

D. Nielsen, D. Shapiro, 1986, Nucleic acids research.

Purification and characterization of Xenopus laevis vitellogenin messenger RNA.

D. J. Shapiro, H. J. Baker, D. Shapiro, 1977, The Journal of biological chemistry.

High-Throughput Fluorescence Anisotropy Screen for Inhibitors of the Oncogenic mRNA Binding Protein, IMP-1

C. Mao, N. Andruska, Chen Zhang, 2014, Journal of biomolecular screening.

Expression of high levels of human proteinase inhibitor 9 blocks both perforin/granzyme and Fas/Fas ligand-mediated cytotoxicity.

Xinguo Jiang, T. D. Cunningham, D. Shapiro, 2007, Cellular immunology.

Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells

D. J. Shapiro, E. Alarid, X. Jiang, 2007, Oncogene.

Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death

Jingwei Cheng, Jian-hua Zhou, D. Shapiro, 2007, Steroids.

A unique downstream estrogen responsive unit mediates estrogen induction of proteinase inhibitor-9, a cellular inhibitor of IL-1beta- converting enzyme (caspase 1).

A. Krieg, D. J. Shapiro, S. Krieg, 2001, Molecular endocrinology.

Proteinase Inhibitor 9, an Inhibitor of Granzyme B-mediated Apoptosis, Is a Primary Estrogen-inducible Gene in Human Liver Cells*

C. Mao, Stanley Wang, D. Zajchowski, 2000, The Journal of Biological Chemistry.

A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

S. Mousses, B. Park, J. Kim, 2021, Science Translational Medicine.

Anticipatory UPR Activation: A Protective Pathway and Target in Cancer

Liqun Yu, D. J. Shapiro, Mara R. Livezey, 2016, Trends in Endocrinology & Metabolism.

Protein kinase C-α is upregulated by IMP1 in melanoma and is linked to poor survival.

S. Gruber, C. Mao, N. Andruska, 2019, Melanoma research.

Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

B. Katzenellenbogen, B. Park, D. Tripathy, 2021, bioRxiv.

Nuclease sensitivity and DNA methylation in estrogen regulation of Xenopus laevis vitellogenin gene expression.

K. Folger, J. Anderson, M. Hayward, 1983, The Journal of biological chemistry.

Activation of vitellogenin gene transcription is a direct response to estrogen in Xenopus laevis liver.

M. Hayward, M. Brock, D. Shapiro, 1982, Nucleic acids research.

Estrogen Receptor Regulation of Vitellogenin Gene Transcription and Chromatin Structure

D. J. Shapiro, M. Hayward, M. Brock, 1983 .

Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression

Xujuan Yang, C. Mao, Xiaobin Zheng, 2015, Proceedings of the National Academy of Sciences.

Estrogen Control of Vitellogenin Gene Transcription and mRNA Stability

J. Blume, D. Mckearin, D. Nielsen, 1987 .

Anticipatory activation of the unfolded protein response by epidermal growth factor is required for immediate early gene expression and cell proliferation

Liqun Yu, Xiaobin Zheng, N. Andruska, 2016, Molecular and Cellular Endocrinology.

A Noncompetitive Small Molecule Inhibitor of Estrogen-regulated Gene Expression and Breast Cancer Cell Growth That Enhances Proteasome-dependent Degradation of Estrogen Receptor α*

R. Schiff, E. Wilson, S. Nordeen, 2010, The Journal of Biological Chemistry.

Analysis of Estrogen Response Element Binding by Genetically Selected Steroid Receptor DNA Binding Domain Mutants Exhibiting Altered Specificity and Enhanced Affinity*

B. Katzenellenbogen, E. Read, S. Chusacultanachai, 1999, The Journal of Biological Chemistry.

Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis.

D. Shapiro, C. Zhang, 2000, The Journal of biological chemistry.

Repression of endogenous estrogen receptor activity in MCF-7 human breast cancer cells by dominant negative estrogen receptors.

B. Katzenellenbogen, D. Schodin, B. Ince, 1995, Endocrinology.

Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers

B. Katzenellenbogen, B. Park, C. Mao, 2020, Cancers.

In simple synthetic promoters YY1-induced DNA bending is important in transcription activation and repression.

D. J. Shapiro, J. Kim, D. Shapiro, 1996, Nucleic acids research.

A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation

C. Mao, N. Andruska, L. Mahapatra, 2017, Translational oncology.

Antiestrogen Resistant Cell Lines Expressing Estrogen Receptor α Mutations Upregulate the Unfolded Protein Response and are Killed by BHPI

J. Kim, C. Mao, D. J. Shapiro, 2016, Scientific Reports.

HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells.

D. Shapiro, C. Zhang, S. Krieg, 1999, Molecular endocrinology.

High level expression of full-length estrogen receptor in Escherichia coli is facilitated by the uncoupler of oxidative phosphorylation, CCCP

C. Zhang, D. J. Shapiro, K. Glenn, 2000, The Journal of Steroid Biochemistry and Molecular Biology.

A New Small Molecule Inhibitor of Estrogen Receptor α Binding to Estrogen Response Elements Blocks Estrogen-dependent Growth of Cancer Cells*

Jingwei Cheng, E. Wilson, A. Nardulli, 2008, Journal of Biological Chemistry.

In Vitro Fluorescence Anisotropy Analysis of the Interaction of Full-length SRC1a with Estrogen Receptors α and β Supports an Active Displacement Model for Coregulator Utilization*

S. Nordeen, D. J. Shapiro, Chen Zhang, 2007, Journal of Biological Chemistry.

Intrinsically Bent DNA in a Eukaryotic Transcription Factor Recognition Sequence Potentiates Transcription Activation (*)

D J Shapiro, J Kim, S Klooster, 1995, The Journal of Biological Chemistry.

Tamoxifen Induction of CCAAT Enhancer-binding Protein α Is Required for Tamoxifen-induced Apoptosis*

Jingwei Cheng, Jian-hua Zhou, D. Shapiro, 2007, Journal of Biological Chemistry.

Estrogen Receptor Induced DNA Bending

G. Greene, A. Nardulli, D. Shapiro, 1994 .

Production and characterization of monoclonal antibodies to rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

M. Barton, G. Martin, R. Clark, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence and estrogen induction of Xenopus laevis 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

D. Shapiro, H. J. Chen, 1990, The Journal of biological chemistry.

Antiestrogens activate an estrogen receptor mutant exhibiting enhanced binding to the estrogen response element.

H. Xing, S. Haase, D. Shapiro, 1994, Biochemical and Biophysical Research Communications - BBRC.

Analysis of ligand dependence and hormone response element synergy in transcription by estrogen receptor

K. Glenn, G. D. Haan, D. Shapiro, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

In vitro translation and estradiol-17beta induction of Xenopus laevis vitellogenin messenger RNA.

H. J. Baker, D. Stitt, D. Shapiro, 1976, The Journal of biological chemistry.

A transcriptionally active estrogen receptor mutant is a novel type of dominant negative inhibitor of estrogen action.

B. Katzenellenbogen, D. J. Shapiro, E. McInerney, 1996, Molecular endocrinology.

Differential Requirements of Hsp90 and DNA for the Formation of Estrogen Receptor Homodimers and Heterodimers*

E. Powell, Wei Xu, D. J. Shapiro, 2010, The Journal of Biological Chemistry.

A Competitive Inhibitor That Reduces Recruitment of Androgen Receptor to Androgen-responsive Genes*

E. Wilson, M. Cherian, Elizabeth M Wilson, 2012, The Journal of Biological Chemistry.

Transient administration of estradiol-17 beta establishes an autoregulatory loop permanently inducing estrogen receptor mRNA.

M. Barton, D. J. Shapiro, D. Shapiro, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Fluorescence anisotropy microplate assay to investigate the interaction of full-length steroid receptor coactivator-1a with steroid receptors.

S. Nordeen, Chen Zhang, D. Shapiro, 2013, Methods in molecular biology.

An N-terminal deletion mutant of estrogen receptor exhibits increased synergism with upstream activators and enhanced binding to the estrogen response element.

D. Lew, H. Xing, D. Shapiro, 1995, Biochemistry.

Strong and sustained activation of the anticipatory unfolded protein response induces necrotic cell death

Rui Huang, P. Hergenrother, Mara R. Livezey, 2018, Cell Death & Differentiation.

Anticipatory Estrogen Activation of the Unfolded Protein Response is Linked to Cell Proliferation and Poor Survival in Estrogen Receptor α Positive Breast Cancer

Xujuan Yang, William G. Helferich, Xiaobin Zheng, 2014, Oncogene.

Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action

Liqun Yu, C. Mao, Mara R. Livezey, 2016, Steroids.

Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells

B. Katzenellenbogen, J. Katzenellenbogen, J. Flaws, 2016, Molecular and Cellular Endocrinology.

Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer.

Matthew W. Boudreau, T. Fan, P. Hergenrother, 2022, Journal of medicinal chemistry.

Strong and sustained activation of the anticipatory unfolded protein response induces necrotic cell death

Rui Huang, P. Hergenrother, D. J. Shapiro, 2018, Cell Death & Differentiation.

Targeting multidrug-resistant ovarian cancer through estrogen receptor α dependent ATP depletion caused by hyperactivation of the unfolded protein response

E. Nelson, P. Hergenrother, Xiaobin Zheng, 2016, Oncotarget.

DNA bending by nuclear receptors.

A. Nardulli, D. Shapiro, 1993, Receptor.

The role of estrogen receptor in Xenopus laevis vitellogenin gene expression.

D J Shapiro, M A Hayward, M L Brock, 1982, The American journal of physiology.

Estrogen regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and acetyl-CoA carboxylase in xenopus laevis.

B. W. Philipp, D. Shapiro, 1981, The Journal of biological chemistry.

Fluorescence anisotropy microplate assay for analysis of steroid receptor-DNA interactions.

S. Nordeen, D. J. Shapiro, Stanley Wang, 2004, BioTechniques.

RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

Gaoxi Xiao, M. Salto‐Tellez, Yoshiaki Ito, 2012, Oncogene.

A functional serine 118 phosphorylation site in estrogen receptor-alpha is required for down-regulation of gene expression by 17beta-estradiol and 4-hydroxytamoxifen.

Jingwei Cheng, Chen Zhang, D. Shapiro, 2007, Endocrinology.

Estrogen receptor mutants which do not bind 17 beta-estradiol dimerize and bind to the estrogen response element in vivo.

B. Katzenellenbogen, Y. Zhuang, D. Shapiro, 1995, Molecular endocrinology.

Quantitation of estrogen effect on Xenopus laevis albumin mRNA levels by hybridization to cloned albumin cDNA.

B. W. Philipp, D. Shapiro, E. Morgan, 1982, The Journal of biological chemistry.

Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells.

Y. Ling, W. Helferich, Xinguo Jiang, 2008, Endocrinology.

Small Molecule Inhibitors as Probes for Estrogen and Androgen Receptor Action*

C. Mao, D. Shapiro, M. T. Cherian, 2010, The Journal of Biological Chemistry.

A New Small Molecule Inhibitor of Estrogen Receptor α Binding to Estrogen Response Elements Blocks Estrogen-dependent Growth of Cancer Cells*

Jingwei Cheng, E. Wilson, A. Nardulli, 2008, Journal of Biological Chemistry.

Posttranscriptional Suppression of Proto-Oncogene c-fms Expression by Vigilin in Breast Cancer

S. Chambers, I. Menzl, X. Yi, 2010, Molecular and Cellular Biology.

Dexamethasone and estrogen regulate Xenopus laevis albumin mRNA levels.

C. L. Jackson, D. Shapiro, 1986, Biochemical and biophysical research communications.

Improved methods for the assay and activation of 3-h y d roxy-3-m et h y I g I ut a ry I coe nzy m e A reductase

B. W. Philipp, D. Shapiro, 1979 .