Shu-Xian Zhang

PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates

H. Yue, Hong-Yu Hu, Lei-Lei Jiang, 2021, Scientific Reports.

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Hong-Yu Hu, Wenlu Guan, Shu-Xian Zhang, 2022, Journal of cell science.

Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in modulation of huntingtin aggregation.

Hong-Yu Hu, Wen-tian He, Jun-Ye Hong, 2020, The Biochemical journal.

Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis

H. Yue, Hong-Yu Hu, Jun-Ye Hong, 2023, Acta biochimica et biophysica Sinica.