J. Medina

发表

Novel hydroborating agents from silylamine-boranes

J. Soderquist, R. Huertas, J. Medina, 1998 .

MONO- AND DIALKYLBORANE REAGENTS FROM SILYLAMINE-BORANES

J. Soderquist, R. Huertas, J. Medina, 1998 .

Discovery of a new series of Aurora inhibitors through truncation of GSK1070916.

Ramona N Plant, M. A. Hardwicke, J. Axten, 2010, Bioorganic & medicinal chemistry letters.

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK).

L. Shewchuk, S. Rabindran, A. Hassell, 2012, Journal of medicinal chemistry.

9-Borabicyclo[3.3.2]decanes and the asymmetric hydroboration of 1,1-disubstituted alkenes.

A. Z. González, E. González, J. Soderquist, 2008, Journal of the American Chemical Society.

Structure-based design of potent and selective 3-phosphoinositide-dependent kinase-1 (PDK1) inhibitors.

S. Rabindran, N. Campobasso, V. Sudakin, 2011, Journal of medicinal chemistry.

Benzyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate, a versatile intermediate for the synthesis of 3,3-dimethylproline derivatives.

K. Erhard, J. Axten, C. Blackledge, 2008, The Journal of organic chemistry.

Novel silyl-mediated 10-TMS-9-BBD organoborane reagents for asymmetric synthesis

J. Soderquist, Carlos H. Burgos, Karl Matos, 2000 .

Selective 3-phosphoinositide-dependent kinase 1 (PDK1) inhibitors: dissecting the function and pharmacology of PDK1.

J. Medina, 2013, Journal of medicinal chemistry.

High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells

Anthony Della Pietra, J. R. Medina, Xin Zeng, 2021, SLAS discovery : advancing life sciences R & D.

Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening.

Douglas W. Thomson, Zhengrong Zhu, J. Boehm, 2022, Journal of medicinal chemistry.

Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development.

A. Hassell, R. Gampe, J. Axten, 2013, ACS medicinal chemistry letters.

Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery.

J. Briand, N. Campobasso, J. Axten, 2010, ACS medicinal chemistry letters.

Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity.

N. Campobasso, J. Axten, Seth W. Grant, 2012, Bioorganic & medicinal chemistry letters.

A mild and general method for the synthesis of 2-substituted-5-hydroxypyrimidines

J. Axten, J. Medina, T. A. Henry, 2006 .

Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c-MYC Protein Levels in Cells.

J. F. Mack, L. Lafrance, R. Rivero, 2021, Journal of medicinal chemistry.

Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells.

J. F. Mack, Leanna E. Shuster, R. Rivero, 2023, Bioorganic & medicinal chemistry letters.