H. Mahdy

发表

Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

Radwan S. El-Haggar, I. Eissa, N. Masurier, 2022, Journal of enzyme inhibition and medicinal chemistry.

Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors

M. Elsohly, M. Radwan, I. Eissa, 2019, Archiv der Pharmazie.

New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies

Wagdy M. Eldehna, N. El-Deeb, I. Eissa, 2022, Journal of enzyme inhibition and medicinal chemistry.

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies

Mohamed S. Nafie, M. M. Khalifa, I. Eissa, 2021, Journal of enzyme inhibition and medicinal chemistry.

Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies

H. Alkahtani, M. Alanazi, M. S. Taghour, 2021, Archiv der Pharmazie.

New bis([1,2,4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation.

H. Alkahtani, M. Alanazi, I. Eissa, 2021, Bioorganic chemistry.

New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis.

M. Alanazi, Ahmad J. Obaidullah, Nawaf A. Alsaif, 2021, Bioorganic chemistry.

Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma.

M. Elsohly, M. Radwan, I. Eissa, 2020, Bioorganic chemistry.

Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors.

M. Elsohly, M. M. Khalifa, M. Radwan, 2020, Bioorganic & medicinal chemistry.

Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation.

M. Elsohly, M. M. Khalifa, M. Radwan, 2020, Bioorganic chemistry.

Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.

H. Luesch, J. Rocca, Ahmed A Nasser, 2020, Organic & biomolecular chemistry.

Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.

M. Elsohly, M. M. Khalifa, M. Radwan, 2020, Bioorganic chemistry.

Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.

M. Elsohly, M. Radwan, I. Eissa, 2019, Bioorganic chemistry.

Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase

Wael A Alanazi, M. Alanazi, M. S. Taghour, 2021, Molecular Diversity.

Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.

I. Eissa, Ahmed B. M. Mehany, H. Elkady, 2021, Bioorganic chemistry.

Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms

Mohamed A. Abdelrahman, C. Supuran, H. Abdel‐Aziz, 2022, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis, docking, and biological evaluation of some novel 5-chloro-2-substituted sulfanylbenzoxazole derivatives as anticonvulsant agents

M. Ibrahim, Khaled El-Adl, M. Zayed, 2014, Medicinal Chemistry Research.

Screening of Some Sulfonamide and Sulfonylurea Derivatives as Anti-Alzheimer’s Agents Targeting BACE1 and PPARγ

Liu Yang, N. Li, Yan Wang, 2020 .

Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation

M. M. Khalifa, I. Eissa, M. S. Taghour, 2022, Journal of enzyme inhibition and medicinal chemistry.

Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies.

Wael A Alanazi, M. Alanazi, M. S. Taghour, 2021, Bioorganic & medicinal chemistry.

Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5‐[(4‐chloro/2,4‐dichloro)benzylidene]thiazolidine‐2,4‐dione derivatives as VEGFR‐2 inhibitors

Khaled El-Adl, Abdel-Ghany A. El-Helby, Helmy M. Sakr, 2020, Archiv der Pharmazie.

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies

M. M. Khalifa, I. Eissa, M. S. Taghour, 2021, Journal of enzyme inhibition and medicinal chemistry.

Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation

I. Eissa, M. S. Taghour, Ahmed B. M. Mehany, 2022, Molecules.

Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations.

Ibrahim M. Ibrahim, I. Eissa, M. S. Taghour, 2023, Journal of biomolecular structure & dynamics.

RECENT ADVANCES ON PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS.

Helmy M. Sakr, H. Mahdy, Hany Elnagar, 2023, Al-Azhar Journal of Pharmaceutical Sciences.

New pyrimidine-5-carbonitrile derivatives as EGFR inhibitors with anticancer and apoptotic activity: Design, molecular modeling and synthesis

R. Ayyad, H. Mahdy, I. A. Osman, 2022, New Journal of Chemistry.

REVIEW ON THE SIGNIFICANCE OF PYRIMIDINE DERIVATIVES AS POTENT ANTI-ANGIOGENIC VEGFR-2 INHIBITORS

Abdulrahman M. Saleh, M. Khalifa, H. Mahdy, 2023, Al-Azhar Journal of Pharmaceutical Sciences.

Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase.

Wael A Alanazi, M. Alanazi, Ahmad J. Obaidullah, 2021 .

SYNTHESIS AND BIOLOGICAL STUDIES OF SOME NOVEL CYCLODIPHOSPHAZANES

H. A. Mahdy, M. E. Nawawy, Tarek H. Afifp, 1998 .

New thiazolidine-2,4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2023, Computational Biology and Chemistry.

New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations.

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, Future medicinal chemistry.

Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase

Wael A Alanazi, M. Alanazi, Ahmad J. Obaidullah, 2021, Molecular Diversity.

Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

M. M. Khalifa, I. Eissa, M. El-Zahabi, 2023, RSC Advances.

Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2,4-dione derivatives as potential antitumor VEGFR-2 inhibitors

Ibrahim M. Ibrahim, A. Darwish, I. Eissa, 2023, RSC Advances.

Novel Thiazolidine‐2,4‐Dione Derivatives as Potential VEGFR‐2 Inhibitors: Synthesis, Biological Testing, and in Silico Studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2024, ChemistrySelect.

Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: In vitro and in silico studies

A. Metwaly, Dalal Z. Husein, H. Elkady, 2024, Heliyon.