C. L. Newton

发表

Co-expression in vertebrate tissues and cell lines of multiple inositol 1,4,5-trisphosphate (InsP3) receptors with distinct affinities for InsP3.

T. Südhof, C. Newton, G. Mignery, 1994, The Journal of biological chemistry.

P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold.

Youwei Yan, L. Kuo, J. Vacca, 2005, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent and selective macrocyclic thrombin inhibitors.

Youwei Yan, J. Barrow, L. Kuo, 2003, Bioorganic & medicinal chemistry letters.

C6 modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption.

J. Vacca, S. Gardell, S. D. Lewis, 1998, Bioorganic & Medicinal Chemistry Letters.

Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles.

Lawrence C Kuo, Daniel R McMasters, Youwei Yan, 2008, Bioorganic & medicinal chemistry letters.

Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position.

Lawrence C Kuo, Daniel R McMasters, James C Barrow, 2003, Bioorganic & medicinal chemistry letters.

Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors.

S. D. Lewis, E. A. Lyle, J. Lynch, 2011, Bioorganic & medicinal chemistry letters.

Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 1: Weakly basic azoles.

S. D. Lewis, B. J. Lucas, A. Naylor-Olsen, 2006, Bioorganic & Medicinal Chemistry Letters.

Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.

Lawrence C Kuo, Daniel R McMasters, James C Barrow, 2004, Journal of medicinal chemistry.

9-hydroxyazafluorenes and their use in thrombin inhibitors.

Youwei Yan, B. Wong, P. Nantermet, 2005, Journal of medicinal chemistry.

Mercaptopyridine-N-oxide, an NADH-fumarate reductase inhibitor, blocks Trypanosoma cruzi growth in culture and in infected myoblasts.

J. Whitfield, R. Docampo, J. Turrens, 1999, FEMS microbiology letters.

Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.

T. Südhof, Christopher, L., 1990, The Journal of biological chemistry.

P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position.

B. Wong, S. D. Lewis, E. A. Lyle, 2011, Bioorganic & medicinal chemistry letters.

Structure of a novel InsP3 receptor.

T. Südhof, Y. Ushkaryov, G. Mignery, 1991, The EMBO journal.