Richard S. Bujaroski

Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

M. Ranson, L. Fliegel, Ashraf Aboelela, 2021, International journal of molecular sciences.

Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor

David John Adams, M. Ranson, J. McArthur, 2022, bioRxiv.

Systematic evaluation of structure-property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride.

David M. Shackleford, M. Ranson, S. Charman, 2021, Bioorganic & medicinal chemistry.

An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis

M. Berney, Natalie Waller, Erik J Hasenoehrl, 2022, Communications Biology.

6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist

I. Jalilian, Ashraf Aboelela, H. Majed, 2022, Biomolecules.

Kinases in cerebral cavernous malformations: Pathogenesis and therapeutic targets.

J. Baell, Xiangjian Zheng, Chunxiao Qi, 2023, Biochimica et biophysica acta. Molecular cell research.

Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

E. Blumwald, M. Kelso, B. Buckley, 2023, Frontiers in Cellular and Infection Microbiology.

A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.

A. Steyn, Kiel Hards, Cara Adolph, 2023, Cell chemical biology.