Adrie D Jones

Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.

Sean P. Brown, A. Cheng, D. Whittington, 2019, Journal of medicinal chemistry.

Stimulus‐Specific Effects of Pentoxifylline on Neutrophil CR3 Expression, Degranulation, and Superoxide Production

J. Padmanabhan, M. Currie, J. Crawford, 1990, Journal of leukocyte biology.

Preclinical Characterization of HPN536, a Trispecific, T-Cell–Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors

S. D. Jones, B. Lemon, P. Baeuerle, 2020, Clinical Cancer Research.

TriTACs, a Novel Class of T-Cell–Engaging Protein Constructs Designed for the Treatment of Solid Tumors

R. Dubridge, B. Lemon, P. Baeuerle, 2020, Molecular Cancer Therapeutics.

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways

C. Su, J. Canon, J. Oliner, 2014, Oncotarget.

A Homogeneous Enzyme Fragment Complementation-Based β-Arrestin Translocation Assay for High-Throughput Screening of G-Protein-Coupled Receptors

K. Olson, T. Wehrman, Xiaoning Zhao, 2008, Journal of biomolecular screening.

Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility.

E. Hu, R. Kunz, N. Chen, 2014, Bioorganic & medicinal chemistry.

Discovery of selective biaryl ethers as PDE10A inhibitors: improvement in potency and mitigation of Pgp-mediated efflux.

E. Hu, Shannon Rumfelt, N. Chen, 2012, Bioorganic & medicinal chemistry letters.