Michael Garrigou

Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) Technology

T. Sawyer, A. Partridge, Pooja Gopal, 2022, Journal of medicinal chemistry.

Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).

M. Hao, Asitha Abeywardane, T. Morwick, 2015, Journal of medicinal chemistry.

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

A. Peier, P. Orth, C. Verma, 2021, bioRxiv.

TBAF-catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: access to arylpyridines and bihetaryl compounds.

M. Whittaker, P. Gros, Heather Tye, 2011, Organic & biomolecular chemistry.