Sijin Liu

Crystal Structure of Human CD47 in Complex with Engineered SIRPα.D1(N80A)

Yongping Song, D. Liu, Jifeng Yu, 2022, Molecules.

SIRPα-Fc fusion protein IMM01 exhibits dual anti-tumor activities by targeting CD47/SIRPα signal pathway via blocking the “don’t eat me” signal and activating the “eat me” signal

Yongping Song, D. Liu, Jifeng Yu, 2022, Journal of Hematology & Oncology.

IMM47, a humanized monoclonal antibody that targets CD24, exhibits exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction and can be used as monotherapy or in combination with anti-PD1 antibodies for cancer immunotherapy

D. Liu, Jifeng Yu, Wenzhi Tian, 2023, Antibody therapeutics.

Combining CD38 antibody with CD47 blockade is a promising strategy for treating hematologic malignancies expressing CD38

D. Liu, Wenzhi Tian, Song Li, 2024, Frontiers in Immunology.