E. Hrincius

发表

Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA

S. Ludwig, H. Humpf, L. Brunotte, 2022, bioRxiv.

Metabolic Modifications by Common Respiratory Viruses and Their Potential as New Antiviral Targets

S. Ludwig, Yvonne Boergeling, Janine J Wilden, 2021, Viruses.

A polyphenol rich plant extract, CYSTUS052, exerts anti influenza virus activity in cell culture without toxic side effects or the tendency to induce viral resistance.

Virginia Korte, Stephan Ludwig, C. Ehrhardt, 2007, Antiviral research.

Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2

A. Hensel, S. Ludwig, G. Hempel, 2022, Pharmaceuticals.

Interplay between influenza A virus and the innate immune signaling.

Thorsten Wolff, Stephan Ludwig, T. Wolff, 2010, Microbes and infection.

The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

R. Fouchier, C. Ehrhardt, S. Ludwig, 2010, PLoS pathogens.

Avian influenza viruses inhibit the major cellular signalling integrator c‐Abl

T. Wolff, C. Ehrhardt, S. Ludwig, 2014, Cellular microbiology.

CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK‐mediated apoptotic responses

T. Wolff, R. Wagner, C. Ehrhardt, 2010, Cellular microbiology.

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

J. McCullers, D. Finkelstein, P. Vogel, 2015, Cell Reports.

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway Graphical Abstract Highlights

J. McCullers, D. Finkelstein, P. Vogel, 2015 .

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

R. Webby, J. McCullers, D. Finkelstein, 2015, The Journal of infectious diseases.

The Two Sides of the Same Coin-Influenza Virus and Intracellular Signal Transduction.

S. Ludwig, Eike R Hrincius, Yvonne Boergeling, 2019, Cold Spring Harbor perspectives in medicine.

Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice.

A. Mellmann, T. Wolff, Henju Marjuki, 2012, The Journal of infectious diseases.

The NF‐κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance

Andrea Rückle, C. Ehrhardt, O. Planz, 2013, Cellular microbiology.

Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood‐derived macrophages

D. Viemann, S. Ludwig, J. Roth, 2012, Journal of leukocyte biology.

A single point mutation (Y89F) within the non-structural protein 1 of influenza A viruses limits epithelial cell tropism and virulence in mice.

J. McCullers, C. Ehrhardt, S. Ludwig, 2012, The American journal of pathology.

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

D. Green, J. McCullers, Gang Wu, 2014, Nature Communications.

Activation of c-jun N-Terminal Kinase upon Influenza A Virus (IAV) Infection Is Independent of Pathogen-Related Receptors but Dependent on Amino Acid Sequence Variations of IAV NS1

W. Nacken, S. Pleschka, T. Wolff, 2014, Journal of Virology.

New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant.

J. McCullers, C. Ehrhardt, S. Ludwig, 2014, The Journal of infectious diseases.

The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses

D. Viemann, O. Planz, S. Ludwig, 2022, Cellular and molecular life sciences : CMLS.

Vitamin A deficiency dysregulates immune responses toward influenza virus and increases mortality after bacterial coinfections.

Amanda P. Smith, J. McCullers, P. Vogel, 2020, The Journal of infectious diseases.

Nonsense‐mediated mRNA decay does not restrict influenza A virus propagation

C. Ehrhardt, S. Ludwig, Eike R Hrincius, 2021, Cellular microbiology.

Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for the creation of a live attenuated vaccine.

S. Ludwig, Eike R Hrincius, C. Scholtissek, 2012, Vaccine.

Late activation of the Raf/MEK/ERK pathway is required for translocation of the respiratory syncytial virus F protein to the plasma membrane and efficient viral replication

C. Ehrhardt, S. Ludwig, Eike R Hrincius, 2018, Cellular microbiology.

The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections

L. Gieselmann, C. Ehrhardt, S. Ludwig, 2020, PloS one.

The NF-kappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus.

Andrea Rückle, C. Ehrhardt, O. Planz, 2013, Antiviral research.

Impact of Staphylococcus aureus Small Colony Variants on Human Lung Epithelial Cells with Subsequent Influenza Virus Infection

C. Ehrhardt, S. Ludwig, Eike R Hrincius, 2020, Microorganisms.

A Plant Extract of Ribes nigrum folium Possesses Anti-Influenza Virus Activity In Vitro and In Vivo by Preventing Virus Entry to Host Cells

C. Ehrhardt, O. Planz, S. Ludwig, 2013, PloS one.

Quantitative Proteomic Analysis of the Influenza A Virus Nonstructural Proteins NS1 and NS2 during Natural Cell Infection Identifies PACT as an NS1 Target Protein and Antiviral Host Factor

R. Webby, A. High, Eike R Hrincius, 2014, Journal of Virology.

Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice

K. Schughart, Eike R Hrincius, D. Anhlan, 2018, The Journal of general virology.

Phosphatidylinositol‐3‐kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig‐I to promote efficient type I interferon production

Stephan Ludwig, C. Ehrhardt, S. Ludwig, 2011, Cellular microbiology.

The NF-kappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus.

Andrea Rückle, C. Ehrhardt, O. Planz, 2013, Antiviral research.