A. Mancini

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Dhara N. Amin, D. Seshasayee, B. Biehs, 2022, Nature.

Understanding TERT Promoter Mutations: A Common Path to Immortality

Jun S. Song, J. Costello, H. T. Rube, 2016, Molecular Cancer Research.

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Chibo Hong, Joseph F. Costello, John K. Wiencke, 2015, Science.

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

J. Doudna, Christof Fellmann, J. Costello, 2020, Proceedings of the National Academy of Sciences.

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.

Jun S. Song, J. Doudna, Christof Fellmann, 2018, Cancer cell.

Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.

J. Costello, R. Pieper, K. Walsh, 2016, Cancer research.

Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis

S. Haas, Z. Modrušan, L. Velten, 2022, Blood advances.

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

C. Mackall, E. Sotillo, H. Balke-Want, 2023, Molecular Cancer.