Y. Abouelhassan

发表

Phenazine Antibiotic‐Inspired Discovery of Bacterial Biofilm‐Eradicating Agents

Hongfen Yang, R. W. Huigens, Y. Abouelhassan, 2019, Chembiochem : a European journal of chemical biology.

Rapid kill assessment of an N-arylated NH125 analogue against drug-resistant microorganisms.

Yousong Ding, Peilan Zhang, Y. Abouelhassan, 2019, MedChemComm.

Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria.

Hussain Yousaf, Hongfen Yang, Aaron T Garrison, 2017, MedChemComm.

Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria.

G. Schultz, Hussain Yousaf, R. W. Huigens, 2017, International journal of antimicrobial agents.

Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms

Shouguang Jin, R. W. Huigens, Fang Bai, 2015 .

Pharmacokinetic Analysis and In Vitro Synergy Evaluation of Cefiderocol, Sulbactam, and Tigecycline in an Extensively Drug-Resistant Acinetobacter baumannii Pneumonia Patient Receiving Continuous Venovenous Hemodiafiltration

D. Nicolau, K. Singaravelu, Emir Kobic, 2022, Open forum infectious diseases.

Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance.

Hongfen Yang, R. W. Huigens, Alejandra Chávez-Riveros, 2019, Journal of medicinal chemistry.

A Phytochemical–Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria

Shouguang Jin, R. W. Huigens, Fang Bai, 2015, ChemMedChem.

A Modular Synthetic Route Involving N-Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents.

Marisa A. Fuse, D. Kallifidas, Shouguang Jin, 2021, Journal of medicinal chemistry.

A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis

D. Kallifidas, Shouguang Jin, H. Luesch, 2017, Scientific Reports.

Plasma and cerebrospinal fluid concentrations of cefiderocol during successful treatment of carbapenem-resistant Acinetobacter baumannii meningitis.

D. Nicolau, R. Gutierrez, Wesley D. Kufel, 2022, The Journal of antimicrobial chemotherapy.

Pharmacokinetic/Pharmacodynamic Optimization of Hospital-Acquired and Ventilator-Associated Pneumonia: Challenges and Strategies.

D. Nicolau, Y. Abouelhassan, 2022, Seminars in respiratory and critical care medicine.

An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.

Hao Tan, D. Kallifidas, Shouguang Jin, 2018, Journal of medicinal chemistry.

Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.

D. Kallifidas, Shouguang Jin, H. Luesch, 2016, Journal of medicinal chemistry.

Transcript Profiling of Nitroxoline-Treated Biofilms Shows Rapid Up-regulation of Iron Acquisition Gene Clusters.

Yanping Zhang, Shouguang Jin, Ke Liu, 2022, ACS infectious diseases.

Transcript Profiling of MRSA Biofilms Treated with a Halogenated Phenazine Eradicating Agent: A Platform for Defining Cellular Targets and Pathways Critical to Biofilm Survival.

Yanping Zhang, Shouguang Jin, R. W. Huigens, 2018, Angewandte Chemie.

Synthetically Tuning the 2-Position of Halogenated Quinolines: Optimizing Antibacterial and Biofilm Eradication Activities via Alkylation and Reductive Amination Pathways.

Shouguang Jin, R. W. Huigens, Fang Bai, 2016, Chemistry.

Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis.

Shouguang Jin, R. W. Huigens, A. Basak, 2018, European journal of medicinal chemistry.

Antimicrobial peptide-inspired NH125 analogues: bacterial and fungal biofilm-eradicating agents and rapid killers of MRSA persisters.

Yousong Ding, Hussain Yousaf, R. W. Huigens, 2017, Organic & biomolecular chemistry.

Identification of N‐Arylated NH125 Analogues as Rapid Eradicating Agents against MRSA Persister Cells and Potent Biofilm Killers of Gram‐Positive Pathogens

Hussain Yousaf, R. W. Huigens, A. Basak, 2017, Chembiochem : a European journal of chemical biology.

Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non-Biofilm Cultures, and Mycobacterium tuberculosis.

V. Mai, D. Kallifidas, Shouguang Jin, 2015, Angewandte Chemie.

Halogenated quinolines discovered through reductive amination with potent eradication activities against MRSA, MRSE and VRE biofilms.

R. W. Huigens, A. Basak, Y. Abouelhassan, 2015, Organic & biomolecular chemistry.

1652. Sulbactam against Acinetobacter baumannii Pneumonia: Pharmacokinetic/Pharmacodynamic Appraisal of Current Dosing Recommendations

D. Nicolau, Kamilia Abdelraouf, J. Kuti, 2022, Open Forum Infectious Diseases.

Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy.

R. W. Huigens, Aaron T Garrison, Gena M. Burch, 2014, Bioorganic & medicinal chemistry letters.

Rapid kill assessment of an N-arylated NH125 analogue against drug-resistant microorganisms.

Yousong Ding, Peilan Zhang, Y. Abouelhassan, 2019, MedChemComm.

Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria.

Hussain Yousaf, Hongfen Yang, Aaron T Garrison, 2017, MedChemComm.