Mark Chen

Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.

Matthew S. Johnson, M. Ultsch, J. Veal, 2022, Journal of medicinal chemistry.

1271 REDUCED DIETARY OMEGA-6:OMEGA-3 RATIO AND 12/15-LIPOXYGENASE DEFICIENCY PROTECT FROM HIGH FAT DIET-INDUCED STEATOHEPATITIS

A. Feldstein, D. Sears, M. Nalbandyan, 2013 .

Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis

Dorothy D. Sears, A. Feldstein, D. Sears, 2014, PloS one.