J. Wittschieben

发表

Loss of DNA Polymerase ζ Enhances Spontaneous Tumorigenesis

R. Wood, D. Kusewitt, L. Robinson, 2010 .

Two‐polymerase mechanisms dictate error‐free and error‐prone translesion DNA synthesis in mammals

Z. Livneh, S. Adar, T. Carell, 2009, The EMBO journal.

Disruption of the developmentally regulated Rev3l gene causes embryonic lethality

R. D. Wood, G. Stamp, R. Wood, 2000, Current Biology.

Mutational analysis of vaccinia DNA topoisomerase defines amino acid residues essential for covalent catalysis.

S. Shuman, J. Wittschieben, 1994, The Journal of biological chemistry.

Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.

S. Shuman, B. O. Petersen, J. Wittschieben, 1998, Nucleic acids research.

Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167.

S. Shuman, J. Wittschieben, 1997, Nucleic acids research.

Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage.

S. Shuman, L. Wang, J. Wittschieben, 1997, Biochemistry.

Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium.

S. Shuman, B. O. Petersen, J. Wittschieben, 1996, Journal of molecular biology.

Loss of DNA polymerase zeta enhances spontaneous tumorigenesis.

R. Wood, D. Kusewitt, L. Robinson, 2010, Cancer research.

DNA polymerase zeta is required for proliferation of normal mammalian cells

R. Wood, Sabine S. Lange, J. Wittschieben, 2012, Nucleic acids research.

Lack of DNA Polymerase θ (POLQ) Radiosensitizes Bone Marrow Stromal Cells In Vitro and Increases Reticulocyte Micronuclei after Total-Body Irradiation

Hong Wang, R. Wood, S. Dertinger, 2009, Radiation research.

DNA polymerase zeta (pol ζ) in higher eukaryotes

R. Wood, Birgitte Ø. Wittschieben, G. Gan, 2008, Cell Research.

Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses

R. Wood, Sabine S. Lange, D. Kusewitt, 2013, Proceedings of the National Academy of Sciences.

Loss of DNA Polymerase ζ Causes Chromosomal Instability in Mammalian Cells

R. Wood, S. Gollin, S. Reshmi, 2006 .

Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells.

R. Wood, S. Gollin, S. Reshmi, 2006, Cancer research.

DNA polymerase zeta (pol zeta) in higher eukaryotes.

R. Wood, G. Gan, B. O. Wittschieben, 2008, Cell research.