Wei Chen

发表

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Qiang Yu, Wei Chen, Edison T Liu, 2007, Genes & development.

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.

Adrian A Canutescu, Roland L Dunbrack, Roland L. Dunbrack, 2005, Developmental cell.

Mediator-dependent nuclear receptor function.

R. Roeder, Wei Chen, 2011, Seminars in cell & developmental biology.

PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1

R. Roeder, T. Nakadai, Y. Ohkuma, 2015, Genes & development.

Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma

Jian-jun Zhao, J. Maciejewski, F. Reu, 2018, Leukemia.

Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene.

R. Roeder, Wei Chen, Qi-heng Yang, 2009, Molecular cell.

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.

B. Chait, R. Roeder, S. Yamamura, 2005, Molecular cell.

HP1 Proteins Are Essential for a Dynamic Nuclear Response That Rescues the Function of Perturbed Heterochromatin in Primary Human Cells

Rugang Zhang, P. Adams, T. Yen, 2006, Molecular and Cellular Biology.

Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci

Rugang Zhang, P. Adams, Wei Chen, 2007, Molecular and Cellular Biology.

A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

R. Roeder, Kıvanç Birsoy, Xiaoting Zhang, 2010, Proceedings of the National Academy of Sciences.

The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation

R. Roeder, Wei Chen, 2007, Nucleic acids research.