G. P. Luke

发表

Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).

David S. Millan, Mark T. Kershaw, K. Bair, 2019, Bioorganic & medicinal chemistry letters.

Synthesis of (S)-5-(1-aminoethyl)-2-(cyclohexylmethoxy)benzamide

D. Holt, G. P. Luke, 1999 .

Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2'-Hydroxypropiophenones and Related beta-Diketones.

Joel Morris, D. Wishka, G. P. Luke, 1996, The Journal of organic chemistry.

Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.

Mark T. Kershaw, S. Ashwell, K. Bair, 2019, Journal of medicinal chemistry.

Diastereoselective additions of enantioenriched .gamma.-(alkoxy)allyl stannanes to .alpha.-alkoxy aldehydes: a synthetic route to carbohydrates

J. A. Marshall, G. P. Luke, 1991 .

Stereoselective total synthesis of bengamide E from glyceraldehyde acetonide and a nonracemic .gamma.-alkoxy allylic stannane

J. A. Marshall, G. P. Luke, 1993 .

Synthesis of Protected Carbohydrate Derivatives Through Homologation of Threose and Erythrose Derivatives with Chiral .gamma.-Alkoxy Allylic Stannanes

J. A. Marshall, B. M. Seletsky, G. P. Luke, 1994 .

LEWIS ACID PROMOTED ADDITIONS OF GAMMA -ALKOXY- AND -(SILYLOXY)CROTYLSTANNANES TO (S)-2-(BENZYLOXY)PROPANAL

J. A. Jablonowski, J. A. Marshall, G. P. Luke, 1994 .

Structure-based design and synthesis of a novel class of Src SH2 inhibitors.

D. Holt, M. Hatada, R. Bohacek, 1999, Bioorganic & medicinal chemistry letters.

Titanium and Boron Mediated Aldol Reactions of β‐Hydroxy Ketones.

G. P. Luke, J. Morris, 1995 .

TITANIUM AND BORON MEDIATED ALDOL REACTIONS OF BETA -HYDROXY KETONES

Joel Morris, G. P. Luke, 1995 .

A titanium (IV) mediated one-pot double condensation synthesis of 5,6-dihydro-4H-pyran-4-ones

D. Wishka, R. B. Gammill, T. Judge, 1997 .

A SIMPLE AND EFFICIENT PREPARATION OF (ARYLPHOSPHINYL)-METHYLPHOSPHONATES

W. Shakespeare, G. P. Luke, 2002 .

Diastereoselective Additions of Enantio-Enriched (γ-Alkoxyallyl) stannanes to α-Alkoxy Aldehydes: A Synthetic Route to Carbohydrates.

J. A. Marshall, G. P. Luke, 1991 .

Formation of 1,3-diynes, 1,3-dienes, and biphenyls via the copper(II) nitrate mediated coupling of organotin compounds

S. Ghosal, K. Kyler, G. P. Luke, 1987 .

A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain.

C. Eyermann, M. Hatada, S. Violette, 2001, Bioorganic & medicinal chemistry letters.

Structure-based design of novel bicyclic nonpeptide inhibitors for the src SH2 domain.

M. Hatada, S. Violette, R. Bohacek, 2000, Journal of medicinal chemistry.

Asymmetric Syntheses and Absolute Stereochemistry of 5,6-Dihydro-α-pyrones, A New Class of Potent HIV Protease Inhibitors

Joel Morris, W. Watt, K. Romines, 1997 .

Asymmetric Syntheses and Absolute Stereochemistry of 5,6‐Dihydro‐α‐pyrones, a New Class of Potent HIV Protease Inhibitors.

Joel Morris, W. Watt, K. Romines, 1997 .

An efficient preparation of beta-aryl-beta-ketophosphonates by the TFAA/H3PO4-mediated acylation of arenes with phosphonoacetic acids.

B. Chenard, C. Seekamp, G. P. Luke, 2008, The Journal of organic chemistry.

Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains.

David S. Millan, T. Herbertz, D. Cardillo, 2017, ACS medicinal chemistry letters.

Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2′-Hydroxypropiophenones and Related β-Diketones.

Joel Morris, D. Wishka, G. P. Luke, 1996 .

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents.

S. Violette, R. Bohacek, T. Sawyer, 2003, Bioorganic & medicinal chemistry letters.