Jing-rui Chai

发表

Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress

Yu-Jun Wang, Jing-Gen Liu, Liu-bin Guo, 2021, Acta Pharmacologica Sinica.

Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory

Yu-Jun Wang, Jing-Gen Liu, Chuan Yu, 2021, Molecular Psychiatry.

SLL-627 Is a Highly Selective and Potent κ Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity.

Wei-Chang Fu, Wei Li, Siyuan Tang, 2022, Journal of medicinal chemistry.

Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and μ Partial Agonist

Yu-Jun Wang, Xue-jun Xu, Yan Ma, 2018, Scientific Reports.

Anteromedial thalamic nucleus to anterior cingulate cortex inputs modulate histaminergic itch sensation

Yu-Jun Wang, Jing-Gen Liu, Wei-Wei Wu, 2020, Neuropharmacology.

Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with κ agonist and μ agonist/antagonist activity.

A. Zhang, J. Neumeyer, Yu-Jun Wang, 2014, European journal of pharmacology.

Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion

Wei Li, Jing Chen, Liming Shao, 2021, Acta Pharmacologica Sinica.

Discovery of an M-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active κ-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile.

Wei-Chang Fu, Wei Li, Lin-qian Yu, 2021, Journal of medicinal chemistry.

Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence.

Junfan Fang, Yu-Jun Wang, Jing-Gen Liu, 2021, Cell reports.

Dissociative role for dorsal hippocampus in mediating heroin self‐administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis

G. Hu, Hu Zhou, Fan Geng, 2017, Addiction biology.

p38 mitogen-activated protein kinase activation in amygdala mediates κ opioid receptor agonist U50,488H-induced conditioned place aversion

M. Li, X. Wu, Y. Liu, 2016, Neuroscience.

Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone.

Wei-Chang Fu, Wei Li, Qiong Xie, 2023, European journal of medicinal chemistry.

Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic.

Wei-Chang Fu, Wei Li, Xiangguo Meng, 2021, Journal of Medicinal Chemistry.

Antinociceptive activities and mechanism of action of Cepharanthine.

Jing Chen, Yu-Jun Wang, Jing-Gen Liu, 2022, Biochemical and biophysical research communications.