Hongzhuan Chen

发表

Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Guanghao Zhu, Mengge Wang, Lili Chen, 2022, Bioorganic Chemistry.

A Multifunctional (-)-Meptazinol-Serotonin Hybrid Ameliorates Oxidative Stress-Associated Apoptotic Neuronal Death and Memory Deficits via Activating the Nrf2/Antioxidant Enzyme Pathway

Lin Zhao, Yu Qiu, Xiaofang Tan, 2023, Oxidative medicine and cellular longevity.

Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid.

Houkai Li, Lili Sheng, N. Zheng, 2023, Pharmacological research.

Sustainable utilization of precious Chinese medicines: challenges and the road ahead.

Guangbo Ge, Haiying Li, Jiahao Gong, 2022, Chinese Journal of Natural Medicines.

Evolution of drug regulations and regulatory innovation for anticancer drugs in China

Yu Qin, Han Yang, W. Xie, 2022, Acta pharmaceutica Sinica. B.

An open-label, pharmacokinetic study of lenalidomide and dexamethasone therapy in previously untreated multiple myeloma (MM) patients with various degrees of renal impairment – validation of official dosing guidelines

S. Trudel, D. Reece, A. Prica, 2020, Leukemia & lymphoma.

Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma

Jun Chen, Qingxiang Song, Yukun Huang, 2023, Nature Communications.

Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1.

S. Dooley, B. Kobe, Q. Zhai, 2023, Journal of hepatology.

Tachyplesin I and its derivatives: A pharmaco-chemical perspective on their antimicrobial and antitumor potential

Xin Luan, Ye Wu, Jinmei Jin, 2022, Expert opinion on drug discovery.

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Qian Zhang, W. Zhang, A. Caflisch, 2022, International Journal of Biological Macromolecules.

Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking

Lanxue Zhao, Shiqi Wang, Yi-Fei Hou, 2023, International journal of molecular sciences.

FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy.

Danmei Yu, Xin Luan, Jiani Lu, 2023, Biochemical pharmacology.

Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy.

Xiaoxia Liu, Xin Luan, Ye Wu, 2023, European journal of medicinal chemistry.