Wenchao Xu

Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure

Jia Chen, Jia Wei, X. Sun, 2022, Nature Communications.

The HDAC6-RNF168 axis regulates H2A/H2A.X ubiquitination to enable double-strand break repair

Wei-Guo Zhu, Xingzhi Xu, Yuan Tian, 2023, Nucleic acids research.

PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair.

Yuan Tian, Xiaopeng Lu, Bin Peng, 2023, Nature Structural & Molecular Biology.

The ARID1A-METTL3-m6A axis ensures effective RNase H1-mediated resolution of R-loops and genome stability.

M. Gullerová, Yuan Tian, Xiangyu Liu, 2024, Cell reports.