J. Gonçalves

发表

HIV-1 Vif Interaction with APOBEC3 Deaminases and its Characterization by a New Sensitive Assay

A. C. Santos, N. Saraiva, Íris Cadima-Couto, 2011, Journal of Neuroimmune Pharmacology.

Camphor-based CCR5 blocker lead compounds – a computational and experimental approach

J. Goncalves, M. C. Justino, G. Justino, 2016 .

Airway Administration of Bacterial Lysate OM-85 Protects Mice Against Respiratory Syncytial Virus Infection

R. Stein, A. P. D. de Souza, C. Pasquali, 2022, Frontiers in Immunology.

KSHV Latency in Transformed B-cells: The Role of LANA1 as a Therapeutic Target

Sofia Corte-Real, J. Goncalves, Lídia Fonseca, 2008 .

miRNA profiling of human naive CD4 T cells links miR‐34c‐5p to cell activation and HIV replication

Andreia J. Amaral, J. A. Guerra-Assunção, A. E. Sousa, 2017, The EMBO journal.

Is prnt a Pseudogene? Identification of Ram Prt in Testis and Ejaculated Spermatozoa

A. Viegas, A. Domingos, C. C. Marques, 2012, PloS one.

Intrabody-based Mapping of Latency-associated Nuclear Antigen from Kaposi's Sarcoma-associated Herpesvirus Show Conserved Epitopes for Viral Latency Inhibition

C. Barbas, Sofia Corte-Real, Lídia Fonseca, 2010 .

latency antigen inhibit viral persistence in lymphoma cells Intrabodies targeting the Kaposi sarcoma-associated herpesvirus

C. Barbas, P. Moore, Sofia Corte-Real, 2008 .

Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.

C. Barbas, P. Moore, Yuan Chang, 2005, Blood.

Yuan latency antigen inhibit viral persistence in lymphoma cells Intrabodies targeting the Kaposi sarcoma – associated herpesvirus

C. Barbas, P. Moore, Sofia Corte-Real, 2005 .

Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity.

I. Barahona, J. Moniz-Pereira, F. Aires da Silva, 2004, Journal of molecular biology.

HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E. coli by a similar mechanism of action.

Sylvie Rato, F. Aires da Silva, Mariana Santa-Marta, 2007, Molecular immunology.

Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic Approaches

A. Godinho-Santos, J. Goncalves, Mariana Santa-Marta, 2013, Front. Immunol..

Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells

Nir Hacohen, Catarina Moita, N. Hacohen, 2010, PloS one.

Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains

D. Gabuzda, X. Yang, B. Shi, 1995, Journal of virology.

Cell type-specific targeting with sindbis pseudotyped lentiviral vectors displaying anti-CCR5 single-chain antibodies.

F. Aires da Silva, Sofia Corte-Real, J. Gonçalves, 2005, Human gene therapy.

Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?

J. Goncalves, Íris Cadima-Couto, J. Gonçalves, 2010, Advances in virology.

HIV-1 Vif and APOBEC3G: Multiple roads to one goal

J. Goncalves, Mariana Santa-Marta, J. Gonçalves, 2004, Retrovirology.

Synthetic antibody discovery against native antigens by CRISPR/Cas9-library generation and endoplasmic reticulum screening

F. Aires-da-Silva, Sofia Corte-Real, J. Ministro, 2020, Applied Microbiology and Biotechnology.

CIB1 and CIB2 are HIV-1 helper factors involved in viral entry

F. Mammano, A. Hance, J. Gonçalves, 2016, Scientific Reports.

Origin, phylogeny, variability and epitope conservation of SARS-CoV-2 worldwide

J. Vítor, E. Anes, F. Vale, 2021, Virus Research.

Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors

C. Barbas, T. Gaj, Mariana Santa-Marta, 2016, PloS one.

Subcellular localization of the Vif protein of human immunodeficiency virus type 1

P. Jallepalli, J. Goncalves, D. Gabuzda, 1994, Journal of virology.

Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation.

J. Goncalves, Mariana Santa-Marta, D. Gabuzda, 2004, Genes & development.

Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells

C. Barbas, Mariana Santa-Marta, Catarina Cunha-Santos, 2020, Molecular therapy. Methods & clinical development.

APOBEC3B Potently Restricts HIV-2 but Not HIV-1 in a Vif-Dependent Manner

K. Strebel, S. Bandarra, I. Barahona, 2021, Journal of virology.

Phosphorylation of Vif and Its Role in HIV-1 Replication (*)

J. Goncalves, D. Gabuzda, Xiaoyu Yang, 1996, The Journal of Biological Chemistry.

Inhibition of Human Immunodeficiency Virus Type 1 Replication with Artificial Transcription Factors Targeting the Highly Conserved Primer-Binding Site

Ben Berkhout, Carlos F. Barbas, David J. Segal, 2006, Journal of Virology.

Functional Analysis of Vif Protein Shows Less Restriction of Human Immunodeficiency Virus Type 2 by APOBEC3G

A. Pombo, I. Barahona, J. Moniz-Pereira, 2005, Journal of Virology.

Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening

C. Barbas, João André Carriço, J. Correia, 2021, Pharmaceutics.

Recombinant Antibodies as Therapeutic Agents

F. Aires da Silva, Sofia Corte-Real, J. Goncalves, 2012, BioDrugs.

Development of Antibody Fragments for Therapeutic Applications

Sofia Corte-Real, J. Goncalves, F. Silva, 2011 .

Role of Vif in human immunodeficiency virus type 1 reverse transcription

Y. Korin, J. Zack, D. Gabuzda, 1996, Journal of virology.

Functional Neutralization of HIV-1 Vif Protein by Intracellular Immunization Inhibits Reverse Transcription and Viral Replication*

C. Barbas, R. Malhó, J. Goncalves, 2002, The Journal of Biological Chemistry.

New LncRNAs in Chronic Hepatitis C progression: from fibrosis to hepatocellular carcinoma

Marina C Costa, F. Enguita, A. C. Ferrasi, 2020, Scientific Reports.

Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates

Pedro M. P. Gois, J. Correia, V. Neves, 2023, Scientific Reports.

Recombinant antibodies as therapeutic agents: pathways for modeling new biodrugs.

F. Aires da Silva, Sofia Corte-Real, J. Gonçalves, 2008, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.

Ubiquitin-fusion as a strategy to modulate protein half-life: A3G antiviral activity revisited.

M. Kotler, Roni Nowarski, A. Freitas-Vieira, 2009, Virology.

Attenuation of HIV-1 Replication in Primary Human Cells with a Designed Zinc Finger Transcription Factor*

David J Segal, João Gonçalves, C. Barbas, 2004, Journal of Biological Chemistry.

Ultrastructure of HIV-1 genomic RNA.

S. Höglund, A. Panganiban, D. Gabuzda, 1997, Virology.

Piezoelectric biosensors for biorecognition analysis: application to the kinetic study of HIV-1 Vif protein binding to recombinant antibodies.

J. Encarnação, G. Ferreira, R. Rodrigues, 2007, Journal of biotechnology.

Rapid, multiplex detection of SARS-CoV-2 using isothermal amplification coupled with CRISPR-Cas12a

J. Gonçalves, A. Cascalheira, D. Figueiredo, 2023, Scientific Reports.

Recombinant single-chain variable fragment and single domain antibody piezoimmunosensors for detection of HIV1 virion infectivity factor.

F. Aires da Silva, J. Encarnação, G. Ferreira, 2007, Biosensors & bioelectronics.

HIV-1 Vif Can Directly Inhibit Apolipoprotein B mRNA-editing Enzyme Catalytic Polypeptide-like 3G-mediated Cytidine Deamination by Using a Single Amino Acid Interaction and Without Protein Degradation*

Mariana Santa-Marta, F. A. da Silva, J. Gonçalves, 2005, Journal of Biological Chemistry.

Synthetic antibody discovery against native antigens by CRISPR/Cas9-library generation and endoplasmic reticulum screening

F. Aires-da-Silva, Sofia Corte-Real, J. Ministro, 2020, Applied Microbiology and Biotechnology.

Recombinant rabbit single‐chain antibodies bind to the catalytic and C‐terminal domains of HIV‐1 integrase protein and strongly inhibit HIV‐1 replication

C. Barbas, D. Harrich, R. Craigie, 2012, Biotechnology and applied biochemistry.

Assessing combinatorial strategies to multimerize libraries of single‐domain antibodies

F. Aires da Silva, J. Goncalves, A. Freitas-Vieira, 2012, Biotechnology and applied biochemistry.