G. Hornby

发表

Synthesis and biological evaluation of novel compounds within a class of 3-aminochroman derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, D. Huryn, C. Beyer, 2006, Journal of medicinal chemistry.

The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices.

F. Liu, K. Marquis, M. Bowlby, 2006, European journal of pharmacology.

Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, J. Ellingboe, L. Schechter, 2010, Bioorganic & medicinal chemistry letters.

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, L. Schechter, D. Smith, 2006, Bioorganic & medicinal chemistry letters.

Studies towards the next generation of antidepressants. Part 4: derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor.

Richard E Mewshaw, L. Schechter, D. Smith, 2005, Bioorganic & medicinal chemistry letters.

Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists.

B. Harrison, C. Beyer, G. Stack, 2009, Journal of medicinal chemistry.

Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2.

B. Harrison, Minsheng Zhang, A. Failli, 2008, Journal of medicinal chemistry.

Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.

Xiaojie Shi, Richard E Mewshaw, L. Schechter, 2004, Journal of medicinal chemistry.

Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.

B. Harrison, D. Huryn, L. Schechter, 2008, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of benzodioxanylpiperazine derivatives as potent serotonin 5-HT(1A) antagonists: the discovery of Lecozotan.

B. Harrison, D. Huryn, W. Childers, 2005, Journal of medicinal chemistry.

Differential and Synergistic Effects of Selective Norepinephrine and Serotonin Reuptake Inhibitors in Rodent Models of Pain

L. Leventhal, M. Brandt, K. Rogers, 2007, Journal of Pharmacology and Experimental Therapeutics.

Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.

K. Marquis, J. Brennan, G. Stack, 2006, European Journal of Pharmacology.

Novel pyridyl-fused 3-amino chroman derivatives with dual action at serotonin transporter and 5-HT1A receptor.

B. Harrison, G. Stack, L. Schechter, 2007, Bioorganic & medicinal chemistry letters.

Probing the Ligand-binding Domain of the mGluR4 Subtype of Metabotropic Glutamate Receptor*

Xi-Ping Huang, D. Hampson, H. Thøgersen, 1999, The Journal of Biological Chemistry.

Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT1A receptor antagonist and potential novel antidepressant

R. Magolda, J. Malberg, S. Rosenzweig-Lipson, 2009, British journal of pharmacology.