Natalie Wellaway

Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.

Darren L. Poole, I. Wall, P. Bamborough, 2022, Journal of medicinal chemistry.

Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.

P. Rowland, C. Jamieson, Simon Peace, 2016, Journal of medicinal chemistry.

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.

Michelle C. Schaeffer, Carol A. Capriotti, Paul E. Lamoureux, 2019, Journal of medicinal chemistry.

Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.

M. Convery, P. Rowland, Simon Peace, 2018, Journal of medicinal chemistry.

Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.

Birgit Dümpelfeld, James M. Woolven, S. Teague, 2021, Journal of medicinal chemistry.

A practical drug discovery project at the undergraduate level.

J. Liddle, M. Fray, D. Coe, 2013, Drug discovery today.

Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity.

I. McLay, Hawa Diallo, I. Uings, 2011, Bioorganic & medicinal chemistry letters.

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.

Darren L. Poole, Tony W Dean, I. Wall, 2020, Journal of medicinal chemistry.

Synthesis of arrays using low molecular weight MPEG-assisted Mitsunobu reaction.

R. Hartley, S. Sollis, A. Cooper, 2011, ACS combinatorial science.