Rui Sousa-Luis

Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy

Luciano E Marasco, A. Krainer, A. Kornblihtt, 2022, Cell.

POINT technology illuminates the processing of polymerase-associated intact nascent transcripts

H. Kimura, M. Carmo-Fonseca, N. Proudfoot, 2020, bioRxiv.

Transcriptome profiling of human pluripotent stem cell‐derived cerebellar organoids reveals faster commitment under dynamic conditions

Tiago G Fernandes, M. Carmo-Fonseca, J. Cabral, 2021, Biotechnology and bioengineering.

Transcriptome profiling of human pluripotent stem cell-derived cerebellar organoids reveals faster commitment under dynamic conditions

Tiago G Fernandes, M. Carmo-Fonseca, J. Cabral, 2021, bioRxiv.

Towards a combined therapy for spinal muscular atrophy based on opposing effects of an antisense oligonucleotide on chromatin and splicing

Luciano E Marasco, A. Krainer, A. Kornblihtt, 2021, bioRxiv.

Pseudouridylation: A new player in co-transcriptional splicing regulation.

M. Carmo-Fonseca, Rui Sousa-Luis, 2022, Molecular cell.