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A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK.

A. Hingorani, S. Haydock, N. Stephens, 1999, Circulation.

A Randomised Controlled Trial of Vitamin E in Patients with Coronary Disease: The Cambridge Heart Antioxidant Study (CHAOS)

M. Brown, P. Schofield, M. J. Mitchinson, 1996 .