Malkeet Kumar

发表

New Verapamil Analogs Inhibit Intracellular Mycobacteria without Affecting the Functions of Mycobacterium-Specific T Cells

K. Chibale, Asmira Selimovic, G. Abate, 2015, Antimicrobial Agents and Chemotherapy.

Design, Synthesis, and Evaluation of Novel Hybrid Efflux Pump Inhibitors for Use against Mycobacterium tuberculosis.

K. Chibale, D. Warner, G. Abate, 2016, ACS infectious diseases.

New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase.

S. Fienberg, K. Chibale, Dale Taylor, 2020, ACS infectious diseases.

Five Solid Forms of a Potent Imidazopyridazine Antimalarial Drug Lead: A Preformulation Study

K. Chibale, S. Bourne, T. Noonan, 2019, Crystal Growth & Design.

Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse Malaria Infection Model.

K. Chibale, T. Egan, Dale Taylor, 2022, Journal of medicinal chemistry.

Synthesis, docking and in vitro antimalarial evaluation of bifunctional hybrids derived from β-lactams and 7-chloroquinoline using click chemistry.

Vipan Kumar, M. P. Mahajan, J. Gut, 2012, Bioorganic & medicinal chemistry letters.

Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical Antimalarials.

K. Chibale, T. Egan, John Okombo, 2023, ACS infectious diseases.

Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.

K. Chibale, T. Egan, Dale Taylor, 2018, ACS infectious diseases.

Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c.

K. Chibale, D. Warner, Kawaljit Singh, 2014, Bioorganic & medicinal chemistry letters.

Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against Plasmodium falciparum In Vitro.

K. Chibale, Dale Taylor, L. Birkholtz, 2021, ACS medicinal chemistry letters.

Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis.

K. Chibale, G. Abate, Kawaljit Singh, 2017, Bioorganic & medicinal chemistry.