Ciaran M Lee

Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity

Ciaran M Lee, Timothy H Davis, Gang Bao, 2018, Experimental physiology.

Tools for experimental and computational analyses of off-target editing by programmable nucleases

Ciaran M Lee, Timothy H Davis, Gang Bao, 2020, Nature Protocols.

Design and Validation of CRISPR/Cas9 Systems for Targeted Gene Modification in Induced Pluripotent Stem Cells.

Ciaran M Lee, Timothy H Davis, Gang Bao, 2017, Methods in molecular biology.

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

Ciaran M Lee, Thomas J Cradick, Gang Bao, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery.

Gang Bao, Ciaran M Lee, Hae-Won Kim, 2017, Chemical reviews.

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells

Gang Bao, Ciaran M Lee, Thomas J Cradick, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human haematopoietic stem and progenitor cells

Gang Bao, Shuqi Yan, Ciaran M Lee, 2018, Nature Medicine.

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

Jing Zhao, Gang Bao, Ciaran M Lee, 2016, American journal of human genetics.

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Peng Qiu, Gang Bao, Ciaran M Lee, 2014, Molecular therapy. Nucleic acids.