J. McGivan

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Identification of a plasma membrane glutamine transporter from the rat hepatoma cell line H4-IIE-C3.

D. Meredith, M. Pollard, J. McGivan, 2002, The Biochemical journal.

The oligomeric structure of renal aminopeptidase N from bovine brush-border membrane vesicles

S. Plakidou-Dymock, J. McGivan, Stella Plakidou-Dymock, 1993, Biochimica et Biophysica Acta (BBA) - Biomembranes.

On the coupling between the transport of phosphate and adenine nucleotides in rat liver mitochondria.

M. Klingenberg, K. Grebe, J. McGivan, 1971, Biochemical and biophysical research communications.

THE ANION TRANSPORTING SYSTEMS OF MITOCHONDRIA AND THEIR BIOCHEMICAL SIGNIFICANCE

M. Crompton, J. Chappell, J. McGivan, 1972 .

Expression and activity of the glutamate transporter EAAT2 in cardiac hypertrophy: implications for ischaemia reperfusion injury

N. King, Hua Lin, M. Saadeh Suleiman, 2006, Pflügers Archiv.

The action of certain antibiotics on mitochondrial, erythrocyte and artificial phospholipid membranes. The role of induced proton permeability.

P. Henderson, J. Chappell, J. Mcgivan, 1969, The Biochemical journal.

Avenaciolide: a specific inhibitor of glutamate transport in rat liver mitochondria.

J. Chappell, J. McGivan, 1970, The Biochemical journal.

The effects L-leucine on the synthesis of urea, glutamate and glutamine by isolated rat liver cells.

J. Chappell, J. Mcgivan, J. M. Mourão, 1975, The Biochemical journal.

Mitochondrial metabolism of glutamine and glutamate and its physiological significance.

Z. Kovačević, J. McGivan, 1983, Physiological reviews.

Distinct effects of glucagon and vasopressin on proline metabolism in isolated hepatocytes. The role of oxoglutarate dehydrogenase.

J. Staddon, J. Mcgivan, J. McGivan, 1984, The Biochemical journal.

The transport of branched‐chain amino acids into isolated rat liver cells

J. Mcgivan, N. Bradford, J. Mendes-Mourrão, 1977, FEBS letters.

A rapid method for the reconstitution of Na+-dependent neutral amino acid transport from bovine renal brush-border membranes.

A. Lynch, J. McGivan, 1987, The Biochemical journal.

On the metabolic function of glutamate dehydrogenase in rat liver

J. Chappell, J. McGivan, 1975, FEBS letters.

Relationship between the expression of hepatic but not testicular 3beta-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue.

J. Wood, O. Doran, F. Whittington, 2006, Journal of animal science.

Amino acid deprivation leads to the emergence of System A activity and the synthesis of a specific membrane glycoprotein in the bovine renal epithelial cell line NBL-1.

C. Soler, A. Felipe, J. McGivan, 1992, The Biochemical journal.

Regulation of the glutamate transporter by amino acid deprivation and associated effects on the level of EAAC1 mRNA in the renal epithelial cell line NBL-I.

S. Plakidou-Dymock, J. McGivan, 1993, The Biochemical journal.

Acetaldehyde binds to liver cell membranes without affecting membrane function.

R. Barry, M. Hayes, J. McGivan, 1984, Gut.

Adaptive regulation of Na(+)-dependent phosphate transport in the bovine renal epithelial cell line NBL-1. Identification of the phosphate transporter as a 55-kDa glycoprotein.

C. Helps, J. Mcgivan, J. McGivan, 1991, European journal of biochemistry.

Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease.

R. Barry, J. McGivan, 1985, Gut.

The detection of acetaldehyde/liver plasma membrane protein adduct formed in vivo by alcohol feeding.

A. Williams, J. Mcgivan, R. Barry, 2008, Liver.

Acetaldehyde alone mayinitiate hepatocellular damage inacute alcoholic liver disease

R. Barry, J. McGivan, 1985 .

Characteristics of the transport of alanine, serine and glutamine across the plasma membrane of isolated rat liver cells.

S. Joseph, J. Mcgivan, N. Bradford, 1978, The Biochemical journal.

Conditions for activity of glutaminase in kidney mitochondria.

Z. Kovačević, J. Chappell, J. McGivan, 1970, The Biochemical journal.

Hyperosmolarity leads to an increase in derepressed system A activity in the renal epithelial cell line NBL-1.

C. Soler, A. Felipe, M. Pastor-Anglada, 1993, The Biochemical journal.

The transport of alanine and glutamine into isolated rat intestinal epithelial cells.

J. Mcgivan, N. Bradford, J. McGivan, 1982, Biochimica et biophysica acta.

Effects of ATP and adenosine addition on activity of oxoglutarate dehydrogenase and the concentration of cytoplasmic free Ca2+ in rat hepatocytes.

J. Staddon, J. Mcgivan, J. McGivan, 1985, European journal of biochemistry.

Characteristics of aspartate deamination by the puring nucleotide cycle in the cytosol fraction of rat liver.

K. Moss, J. McGivan, 1975, The Biochemical journal.

The transport of glutamine into mammalian cells.

J. Mcgivan, C. Bungard, J. McGivan, 2007, Frontiers in bioscience : a journal and virtual library.

Short-term stimulation of Na+-dependent amino acid transport by dibutyryl cyclic AMP in hepatocytes. Characteristics and partial mechanism.

S. Moule, J. Mcgivan, N. Bradford, 1987, The Biochemical journal.

Characterisation of androstenone metabolism in pig liver microsomes.

J. Wood, E. Doran, J. Mcgivan, 2004, Chemico-biological interactions.

Glutamine Transport Across Biological Membranes

Z. Kovačević, J. McGivan, 1984 .

Quantitative characteristics of glutamate transport in rat liver mitochondria.

J. Mcgivan, N. Bradford, J. McGivan, 1973, The Biochemical journal.

Techniques Used in the Study of Plasma Membrane Amino Acid Transport

J. Mcgivan, J. McGivan, 1992 .

Differential effects of starvation on alanine and glutamine transport in isolated rat hepatocytes.

J. Mcgivan, M. Hayes, J. McGivan, 1982, The Biochemical journal.

Effect of L-leucine on the nitrogen metabolism of isolated rat liver mitochondria.

M. Crompton, J. Chappell, J. Mcgivan, 1973, The Biochemical journal.

The relationship between adipose tissue skatole levels, rates of hepatic microsomal skatole metabolism and hepatic cytochrome P450IIE1 expression in two breeds of pig

Elena Doran, Jan Wood, F. W. Whittington, 2002 .

Epidermal growth factor stimulates the phosphorylation of pyruvate kinase in fleshly isolated rat hepatocytes

S. Moule, J. McGivan, J.D. McGivan, 1991 .

Regulation of the plasma membrane potential in hepatocytes--mechanism and physiological significance.

S. Moule, J. Mcgivan, J. McGivan, 1990, Biochimica et biophysica acta.

Mechanism of the stimulation of serine and alanine transport into isolated rat liver cells by bicarbonate ions.

J. Mcgivan, J. McGivan, 1979, The Biochemical journal.

Glutaminase isoform expression in cell lines derived from human colorectal adenomas and carcinomas.

J. Mcgivan, A. Turner, J. McGivan, 2003, The Biochemical journal.

Regulatory and molecular aspects of mammalian amino acid transport.

M. Pastor-Anglada, J. Mcgivan, J. McGivan, 1994, The Biochemical journal.

A role for aminopeptidase N in Na(+)-dependent amino acid transport in bovine renal brush-border membranes.

M. Tanner, S. Plakidou-Dymock, J. McGivan, 1993, The Biochemical journal.

Correlation between H+ and anion movement in mitochondria and the key role of the phosphate carrier.

M. Klingenberg, J. Mcgivan, J. McGivan, 1971, European journal of biochemistry.

The bovine renal epithelial cell line NBL-1 expresses a broad specificity Na(+)-dependent neutral amino acid transport system (System Bo) similar to that in bovine renal brush border membrane vesicles.

J. Mcgivan, F. A. Doyle, J. McGivan, 1992, Biochimica et biophysica acta.

Regulation of high-affinity glutamate transport by amino acid deprivation and hyperosmotic stress.

B. Nicholson, J. Mcgivan, J. McGivan, 1999, American journal of physiology. Renal physiology.

Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes.

J. Wood, F. W. Whittington, E. Doran, 2002, Chemico-biological interactions.

Adaptive changes in the capacity of systems used for the synthesis of citrulline in rat liver mitochondria in response to high- and-low-protein diets.

J. Chappell, J. Mcgivan, N. Bradford, 1974, The Biochemical journal.

Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers.

J. Mcgivan, C. Bungard, J. McGivan, 2005, Archives of biochemistry and biophysics.

Glutamine availability up-regulates expression of the amino acid transporter protein ASCT2 in HepG2 cells and stimulates the ASCT2 promoter.

J. Mcgivan, C. Bungard, J. McGivan, 2004, The Biochemical journal.

Glutamine availability upregulates expression of the amino acid transporter protein ASCT 2 in HepG 2 cells and stimulates the ASCT 2 promoter

C. Bungard, J. McGivan, 2004 .

Characteristics of the activation of glutaminase by ammonia in sonicated rat liver mitochondria.

J D McGivan, N M Bradford, N. Bradford, 1983, Biochimica et biophysica acta.

The stimulation of glutamine hydrolysis in isolated rat liver mitochondria by Mg2+ depletion and hypo-osmotic incubation conditions.

A. Meijer, S. Joseph, J. McGivan, 1981, The Biochemical journal.

The effect of ammonium chloride and glucagon on the metabolism of glutamine in isolated liver cells from starved rats.

S. Joseph, J. Mcgivan, J. McGivan, 1978, Biochimica et biophysica acta.

Bicarbonate stimulation of Na+ transport in liver basolateral plasma membrane vesicles requires the presence of a transmembrane pH gradient.

S. Moule, A. Felipe, J. McGivan, 1990, Biochimica et biophysica acta.

Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig.

C. Haley, A. Archibald, E. Doran, 2005, Animal genetics.

Epidermal growth factor and cyclic AMP stimulate Na+/H+ exchange in isolated rat hepatocytes.

S. Moule, J. Mcgivan, J. McGivan, 1990, European journal of biochemistry.

Breed-associated variations in the sequence of the pig 3beta-hydroxysteroid dehydrogenase gene.

J. Wood, O. Doran, R. Cue, 2007, Journal of animal science.

Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia–reperfusion injury

N. King, M. Suleiman, Hua Lin, 2004, The Journal of physiology.

Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation.

A. Halestrap, N. King, M. Suleiman, 2003, Journal of molecular and cellular cardiology.

A rapid method for the functional reconstitution of amino acid transport systems from rat liver plasma membranes. Partial purification of System A.

A. R. Quesada, J. McGivan, 1988, The Biochemical journal.

Evidence for a single common Na+-dependent transport system for alanine, glutamine, leucine and phenylalanine in brush-border membrane vesicles from bovine kidney.

J. Mcgivan, A. Lynch, J. McGivan, 1987, Biochimica et biophysica acta.

The regulation of carbamoyl phosphate synthase activity in rat liver mitochondria.

J. Mcgivan, J. Mendes-Mourāo, N. Bradford, 1976, The Biochemical journal.

Glucagon and ammonia influence the long-term regulation of phosphate-dependent glutaminase activity in primary cultures of rat hepatocytes.

K. Boon, F. A. Doyle, J. McGivan, 1991, The Biochemical journal.

Factors influencing the inactivation of phosphate-dependent glutaminase in the matrix fraction of rat liver mitochondria.

K. Boon, F. A. Doyle, J. McGivan, 1991, The Biochemical journal.

Stimulation of alanine transport and metabolism by dibutyryl cyclic AMP in the hepatocytes from fed rats. Assessment of transport as a potential rate-limiting step for alanine metabolism.

J. Mcgivan, J. Lacey, J. C. Ramsell, 1981, Biochimica et biophysica acta.

Induction of the stress protein Grp75 by amino acid deprivation in CHO cells does not involve an increase in Grp75 mRNA levels.

J. Mcgivan, R. Heal, J. McGivan, 1997, Biochemical Society transactions.

Evidence for the existence of an ornithine/citrulline antiporter in rat liver mitochondria

J. Mcgivan, N. Bradford, J. McGivan, 1980, FEBS letters.

Increased activity of phosphate-dependent glutaminase in liver mitochondria as a result of glucagon treatment of rats.

S. Joseph, N. Bradford, J. Lacey, 1981, The Biochemical journal.

Rat liver glutaminase. Regulation by reversible interaction with the mitochondrial membrane.

J. Mcgivan, N. Bradford, M. Vadher, 1985, European journal of biochemistry.

Localization and some properties of phosphate-dependent glutaminase in disrupted liver mitochondria.

S. Joseph, J. Mcgivan, J. Lacey, 1980, The Biochemical journal.

Reconstitution and identification of the major Na(+)-dependent neutral amino acid-transport protein from bovine renal brush-border membrane vesicles.

F. A. Doyle, J. McGivan, 1992, The Biochemical journal.

Rat hepatoma cells express novel transport systems for glutamine and glutamate in addition to those present in normal rat hepatocytes.

J. McGivan, 1998, The Biochemical journal.

Induction of calreticulin expression in response to amino acid deprivation in Chinese hamster ovary cells.

R. Heal, J. McGivan, 1998, The Biochemical journal.

Calreticulin--a stress protein induced in the renal epithelial cell line NBL-1 by amino acid deprivation.

S. Plakidou-Dymock, J. McGivan, 1994, Cell calcium.

Regulation of high-affinity glutamate transport by amino acid deprivation and hyperosmotic stress.

B. Nicholson, J. McGivan, 1999, American journal of physiology. Renal physiology.

The effects of ammonium chloride and bicarbonate on the activity of glutaminase in isolated liver mitochondria.

S. Joseph, J. Mcgivan, J. McGivan, 1978, The Biochemical journal.

Cloning, sequence analysis and expression of the cDNA encoding a sodium-dependent phosphate transporter from the bovine renal epithelial cell line NBL-1.

H. Murer, C. Helps, J. McGivan, 1995, European journal of biochemistry.

The use of 36Cl- to measure cell plasma membrane potential in isolated hepatocytes--effects of cyclic AMP and bicarbonate ions.

J. Mcgivan, N. Bradford, M. Hayes, 1985, Biochimica et biophysica acta.

Up-regulation of system A activity by hypertonic shock in CHO-K1 cells and an alanine-resistant mutant.

A. Felipe, M. Pastor-Anglada, J. Casado, 1994, Biochemical Society transactions.

The intramitochondrial location of the glutaminase isoenzymes of pig kidney.

M. Crompton, J. Chappell, J. McGivan, 1973, The Biochemical journal.

Epidermal growth factor, like glucagon, exerts a short-term stimulation of alanine transport in rat hepatocytes.

S. Moule, J. McGivan, 1987, The Biochemical journal.

Evidence for a regulatory protein involved in the increased activity of system A for neutral amino acid transport in osmotically stressed mammalian cells.

A. Felipe, M. Pastor-Anglada, F. Casado, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

J. Wood, E. Doran, W. Tambyrajah, 2004, Archives of biochemistry and biophysics.

Factors influencing the activity of ornithine aminotransferase in isolated rat liver mitochondria.

A. Beavis, J. Mcgivan, N. Bradford, 1977, The Biochemical journal.

The effects of acetylcolletotrichin on the mitochondrial respiratory chain.

B. Foucher, J. Chappell, J. McGivan, 1974, Biochemical Journal.

Mammalian amino acid transporters and their regulation: introduction.

J. McGivan, 1996, Biochemical Society transactions.

Effects of glucagon in vivo on the N-acetylglutamate, glutamate and glutamine contents of rat liver.

J. Staddon, N. Bradford, J. McGivan, 1984, The Biochemical journal.

Induction of High Affinity Glutamate Transport Activity by Amino Acid Deprivation in Renal Epithelial Cells Does Not Involve an Increase in the Amount of Transporter Protein (*)

B. Nicholson, J. McGivan, John D. McGivan, 1996, The Journal of Biological Chemistry.

The intramitochondrial location of the glutaminase isoenzymes of pig kidney.

M. Crompton, J. Chappell, J. McGivan, 1973, The Biochemical journal.

Regulation of amino acid transport in the renal epithelial cell line NBL-1

B. Nicholson, J. McGivan, J. Burston, 1996, Amino Acids.

Regulation of System B0 amino-acid-transport activity in the renal epithelial cell line NBL-1 and concomitant changes in SAAT1 hybridizing transcripts.

M. Tanner, S. Plakidou-Dymock, J. McGivan, 1994, The Biochemical journal.

The transport of metabolites across the mitochondrial membranes.

J. Chappell, J. McGivan, 1972, The Biochemical journal.

Transport of alanine across hepatocyte plasma membranes.

J. McGivan, 1989, Methods in enzymology.

Alanine transport in relation to alanine metabolism in isolated hepatocytes from fed rats.

J. C. Ramsell, J. McGivan, 1980, Biochemical Society transactions.

Characteristics of L-aspartate transport and expression of EAAC-1 in sarcolemmal vesicles and isolated cells from rat heart.

N. King, M. Suleiman, H. Williams, 2001, Cardiovascular research.

Induction of the high-affinity Na(+)-dependent glutamate transport system XAG- by hypertonic stress in the renal epithelial cell line NBL-1.

A. Felipe, M. Pastor-Anglada, J. Casado, 1995, The Biochemical journal.

The rat hepatoma cell line H4‐II‐E‐C3 expresses high activities of the high‐affinity glutamate transporter GLT‐1A

M. Pollard, J. McGivan, John McGivan, 2000, FEBS letters.

Relationships between skatole and androstenone accumulation, and cytochrome P4502E1 expression in Meishan×Large White pigs.

Elena Doran, G. Nute, I. Lean, 2004, Meat science.