A. Aguayo-Orozco

发表

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

J. Rahnenführer, K. Edlund, L. Kuepfer, 2019, Archives of Toxicology.

Population-wide analysis of laboratory tests to assess seasonal variation and the relevance of temporal reference interval modification

S. Brunak, Alejandro Aguayo-Orozco, A. Aguayo-Orozco, 2022, medRxiv.

The use of systems biology in chemical risk assessment

Olivier Taboureau, Søren Brunak, Alejandro Aguayo-Orozco, 2019, Current Opinion in Toxicology.

Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Ulrik Plesner Jacobsen, M. McCarthy, O. Pedersen, 2023, Nature Biotechnology.

Extrapolation of drug induced liver injury responses from cancer cell lines using machine learning approaches

Søren Brunak, Olivier Taboureau, Alejandro Aguayo-Orozco, 2021 .

Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients

Jessica X Hjaltelin, Søren Brunak, Alejandro Aguayo-Orozco, 2020, Nature Communications.

Age‐stratified longitudinal study of Alzheimer's and vascular dementia patients

S. Brunak, Mette Lademann, Alejandro Aguayo-Orozco, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Optimizing drug selection from a prescription trajectory of one patient

S. Brunak, P. Moseley, D. Westergaard, 2021, npj Digital Medicine.

In Silico Systems Pharmacology to Assess Drug's Therapeutic and Toxic Effects.

S. Brunak, K. Audouze, O. Taboureau, 2017, Current pharmaceutical design.

Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets

S. Brunak, C. Geisler, A. Woetmann, 2021, Frontiers in Immunology.

A read-across case study on chronic toxicity of branched carboxylic acids (1): Integration of mechanistic evidence from new approach methodologies (NAMs) to explore a common mode of action.

Thomas E. Exner, E. Benfenati, O. Taboureau, 2021, Toxicology in Vitro.

A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.

Alejandro Aguayo-Orozco, Dilip Narayanan, A. Bach, 2019, Journal of medicinal chemistry.

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes

J. Rahnenführer, K. Edlund, O. Taboureau, 2018, Archives of Toxicology.

sAOP: linking chemical stressors to adverse outcomes pathway networks

Olivier Taboureau, Søren Brunak, Alejandro Aguayo-Orozco, 2019, Bioinform..

Population-wide analysis of hospital laboratory tests to assess seasonal variation and temporal reference interval modification

Alejandro Aguayo-Orozco, Søren Brunak, A. Aguayo-Orozco, 2023, Patterns.

Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity

Søren Brunak, Olivier Taboureau, Frederic Yves Bois, 2018, Front. Genet..

Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity

S. Brunak, F. Bois, O. Taboureau, 2018, Front. Genet..