S. W. Young

发表

High throughput screening for orphan and liganded GPCRs.

J. Reagan, R. Schwandner, Xiaoning Zhao, 2008, Combinatorial chemistry & high throughput screening.

Activation of mitogen‐activated protein kinase by protein kinase C isotypes α, β I and γ, but not ϵ

J. Tavaré, M. Dickens, S. W. Young, 1996 .

Effects of tyrosine kinase inhibitors on protein kinase‐independent systems

J. Tavaré, R. Denton, A. Halestrap, 1993, FEBS letters.

Quantitative analysis of free fatty acids in rat plasma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with meso-tetrakis porphyrin as matrix.

Haiqiang Yu, H. Tian, S. Young, 2006, Analytical biochemistry.

Development of a time-resolved fluorescence resonance energy transfer assay for cyclin-dependent kinase 4 and identification of its ATP-noncompetitive inhibitors.

J. Eksterowicz, R. Emkey, K. Dai, 2012, Analytical biochemistry.

Effect of glucagon on insulin receptor phosphorylation in intact liver cells

J. Tavaré, T. Issad, R. Denton, 1992, FEBS letters.

Development of a high throughput time-resolved fluorescence resonance energy transfer assay for TRAF6 ubiquitin polymerization.

Z. Cao, A. North, Xiong-ying Gao, 2003, Assay and drug development technologies.

Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.

N. Walker, U. Schindler, J. Powers, 2020, ACS medicinal chemistry letters.

An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1.

Rajiv Sharma, J. Anzola, Jinqian Liu, 2007, Analytical biochemistry.

Discovery of Potent and Selective PI3Kγ Inhibitors.

N. Walker, U. Schindler, J. Powers, 2020, Journal of medicinal chemistry.

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen‐activated protein kinase

J. Tavaré, M. Dickens, S. W. Young, 1994, FEBS letters.

Discovery of AB680 - A Potent and Selective Inhibitor of CD73.

N. Walker, N. Sträter, Lijuan Fu, 2020, Journal of medicinal chemistry.

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase.

C. Proud, J. Tavaré, G. Welsh, 1994, The Biochemical journal.

A highly sensitive high-throughput luminescence assay for malonyl-CoA decarboxylase.

J. Zondlo, H. Yamane, Minghan Wang, 2008, Analytical biochemistry.

A Homogeneous Enzyme Fragment Complementation-Based β-Arrestin Translocation Assay for High-Throughput Screening of G-Protein-Coupled Receptors

K. Olson, T. Wehrman, Xiaoning Zhao, 2008, Journal of biomolecular screening.

Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity

A. Becker, J. Powers, A. Udyavar, 2022, Molecular cancer therapeutics.

Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).

N. Walker, U. Schindler, J. Powers, 2021, Journal of medicinal chemistry.

A Generic High-Throughput Screening Assay for Kinases: Protein Kinase A as an Example

Wei Liu, Elissa Swearingen, R. Mallari, 2003, Journal of biomolecular screening.

Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73.

N. Walker, N. Sträter, D. Mandal, 2020, Journal of medicinal chemistry.

Discovery and Characterization of a Potent and Selective Inhibitor for Human Phosphoinositide‐3‐kinase γ

J. Powers, Lixia Jin, Xiaoning Zhao, 2020, The FASEB Journal.

An Exceptionally Potent Inhibitor of Human CD73.

Amber T. Pham, R. G. da Silva, S. W. Young, 2019, Biochemistry.

509 Potent and selective inhibition Of AXL receptor tyrosine kinase for the treatment of cancer

J. Powers, A. Udyavar, S. Cho, 2020, Journal for ImmunoTherapy of Cancer.

Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors.

N. Walker, N. Sträter, J. Powers, 2021, Journal of medicinal chemistry.

Abstract 4980: Altered pan-Ras pathway and activating mutations in EGFR result in elevated CD73 in multiple cancers

A. Udyavar, A. Anderson, D. Direnzo, 2019, Immunology.

Effects of histones on induction of hepatic threonine dehydratase.

J. Irvin, S. W. Young, 1968, Biochimica et Biophysica Acta.

A highly sensitive high-throughput luminescence assay for malonyl-CoA decarboxylase.

J. Zondlo, H. Yamane, Minghan Wang, 2008, Analytical biochemistry.