Kjell A. Svensson

Ensemble Docking Approach to Mitigate Pregnane X Receptor-Mediated CYP3A4 Induction Risk

E. Hembre, J. Rehmel, J. Hao, 2022, J. Chem. Inf. Model..

Safety and Efficacy of Mevidalen in Lewy Body Dementia: A Phase 2, Randomized, Placebo‐Controlled Trial

L. Munsie, M. Brys, K. Biglan, 2021, Movement disorders : official journal of the Movement Disorder Society.

Safety, Tolerability, and Pharmacokinetics of Mevidalen (LY3154207), a Centrally Acting Dopamine D1 Receptor‐Positive Allosteric Modulator (D1PAM), in Healthy Subjects

K. Biglan, W. Kielbasa, D. Wilbraham, 2020, Clinical pharmacology in drug development.

Effects of DPTQ, a novel positive allosteric modulator of the dopamine D1 receptor, on spontaneous eye blink rate and spatial working memory in the nonhuman primate

Graham V. Williams, S. Castner, H. Marston, 2023, Psychopharmacology.

The Dopamine D1 Receptor Positive Allosteric Modulator Mevidalen (LY3154207) Enhances Wakefulness in the Humanized D1 Mouse and in Sleep-Deprived Healthy Male Volunteers

K. Biglan, C. Brittain, A. McCarthy, 2021, The Journal of Pharmacology and Experimental Therapeutics.

Safety, Tolerability, and Pharmacokinetics of Mevidalen (LY3154207), a Centrally Acting Dopamine D1 Receptor–Positive Allosteric Modulator, in Patients With Parkinson Disease

K. Biglan, W. Kielbasa, P. Ardayfio, 2021, Clinical pharmacology in drug development.

Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor

F. Willard, E. Hembre, R. F. Bruns, 2022, Molecular Pharmacology.

An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis

Todd R. Wiernicki, Charles R. Yang, T. Suter, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile.

M. Mohutsky, M. Posada, E. Hembre, 2022, Journal of medicinal chemistry.