Christopher Maclauchlin

发表

Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics.

Sara C. Humphreys, S. Stahl, David G. Belair, 2021, ALTEX.

Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

P. Watkins, S. Siler, P. Fernandes, 2019, Pharmaceutical Research.

Utilizing Drug-Drug Interaction Prediction Tools during Drug Development: Enhanced Decision Making Based on Clinical Risk

Carole E Shardlow, Grant T Generaux, Jackie C Bloomer, 2011, Drug Metabolism and Disposition.

Contribution of Metabolites to P450 Inhibition–Based Drug–Drug Interactions: Scholarship from the Drug Metabolism Leadership Group of the Innovation and Quality Consortium Metabolite Group

W. Humphreys, R. Walsky, C. Prakash, 2015, Drug Metabolism and Disposition.

The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human

M. Manoharan, S. Chong, K. Charissé, 2022, Drug Metabolism and Disposition.

Minireview The Nonclinical Disposition and Pharmacokinetic/ Pharmacodynamic Properties of N -Acetylgalactosamine – Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human S

M. Manoharan, S. Chong, K. Charissé, 2022 .

The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human

M. Manoharan, S. Chong, K. Charissé, 2021, Drug Metabolism and Disposition.

A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction.

D. Mould, K. Keedy, R. Darouiche, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Synthesis and Cytotoxic Action of 1‐Oxoalkyl and 1,2‐Dioxoalkyl‐1,2,4‐triazolidine‐3,5‐diones in Murine and Human Tissue Cultured Cells

I. Hall, R. Izydore, Christopher Maclauchlin, 1999, Archiv der Pharmazie.

Contribution of Metabolites to P 450 Inhibition – Based Drug – Drug Interactions : Scholarship from the Drug Metabolism Leadership Group of the Innovation and Quality Consortium Metabolite Group s

W. Humphreys, R. Walsky, C. Prakash, 2015 .

Human Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for Hepatotoxicity

K. Koch, D. Borts, S. Castellino, 2012, Drug Metabolism and Disposition.

Metabolism, Excretion, and Mass Balance of Solithromycin in Humans

K. Keedy, S. Schneider, P. Fernandes, 2018, Antimicrobial Agents and Chemotherapy.

Clinical and Preclinical Single-Dose Pharmacokinetics of VIR-2218, an RNAi Therapeutic Targeting HBV Infection

G. Robbie, Valerie A. Clausen, E. Mogalian, 2021, Drugs in R&D.

Minireview The Nonclinical Disposition and Pharmacokinetic/ Pharmacodynamic Properties of N -Acetylgalactosamine – Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human S

M. Manoharan, S. Chong, K. Charissé, 2022 .

Human Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for Hepatotoxicity

K. Koch, D. Borts, S. Castellino, 2012, Drug Metabolism and Disposition.