A. Yépes

发表

Discovery of novel neuroprotective cinnamoyl-M30D hybrids targeting Alzheimer’s disease

Edison H Osorio, Wilson Cardona‐G, K. Sierra, 2022, Medicinal Chemistry Research.

Discovery of novel donepezil-M30D hybrids with neuroprotective properties for Alzheimer’s disease treatment

Wilson Cardona‐G, K. Sierra, Rafael Posada-Duque, 2022, Medicinal Chemistry Research.

Proapoptotic Effect and Molecular Docking Analysis of Curcumin–Resveratrol Hybrids in Colorectal Cancer Chemoprevention

T. Naranjo, Wilson Cardona‐G, Andrés F. Yepes, 2022, Molecules.

New class of hybrids based on chalcone and melatonin: a promising therapeutic option for the treatment of colorectal cancer

Wilson Cardona‐G, Angie Herrera-R, Gustavo Moreno, 2021, Medicinal Chemistry Research.

Synthesis and in vitro activity of new tetrahydronaphtho[1,2-b]azepine derivatives against Trypanosoma cruzi and Leishmania chagasi parasites.

C. A. Coronado, P. Escobar, A. Palma, 2009, Bioorganic & medicinal chemistry letters.

Novel Multipotent Amantadine-M30D Hybrids with Highly Selective Butyrylcholinesterase Inhibition and Neuroprotective Effects as Effective Anti-Alzheimer's Agents.

E. Osorio, K. Sierra, Andrés F. Yepes, 2022, ACS chemical neuroscience.

Antiaging activity, molecular docking, and prediction of percutaneous absorption parameters of quinoline–hydrazone hybrids

K. Bravo, E. Osorio, W. Cardona, 2019, Medicinal Chemistry Research.

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids

S. Robledo, M. Carda, Wilson Cardona‐G, 2020 .

Furanchalcone–biphenyl hybrids: synthesis, in silico studies, antitrypanosomal and cytotoxic activities

S. Robledo, I. Velez, E. García, 2019, Medicinal Chemistry Research.

Purple passion fruit seeds (Passiflora edulis f. edulis Sims) as a promising source of skin anti-aging agents: Enzymatic, antioxidant and multi-level computational studies

K. Bravo, Edison H Osorio, Jorge Quintero-Saumeth, 2021 .

S-allylCysteine Ester/Caffeic Acid Amide Hybrids as Promising Antiprotozoal Candidates: Synthesis, Biological Evaluation and Molecular Modeling Studies

S. Robledo, Wilson Cardona‐G, Laura Juliana Prieto, 2022, Brazilian Journal of Pharmaceutical Sciences.

Synthesis, anti-parasitic activity and QSAR study of a new library of polysubstituted tetrahydronaphtho[1,2-b]azepines

R. Enriz, J. Cobo, A. Bahsas, 2018, Medicinal Chemistry Research.

Styrylcoumarin 7-SC2 induces apoptosis in SW480 human colon adenocarcinoma cells and inhibits azoxymethane-induced aberrant crypt foci formation in BALB/c mice

M. Maldonado, T. Naranjo, Wilson Cardona‐G, 2019, Medicinal Chemistry Research.

Antileishmanial and cytotoxic activities of four Andean plant extracts from Colombia

S. Robledo, I. Velez, Wilson Cardona‐G, 2020, Veterinary world.

Synthetic Cannabinoids

K. Nugent, A. Yépes, Brooke Mills, 2015, The American journal of the medical sciences.

Discovery of novel trihybrids based on salicylic acid/isoleucine/ N-acylhydrazone: A promising therapeutic opportunity in colorectal cancer

W. Cardona, Andrés F. Yepes, Gustavo Moreno, 2022, Journal of Applied Pharmaceutical Science.

New Heterofused Thiazolo/Pyrazinedione Hybrids as Promising Building Blocks for Anticancer Drug Development: Synthesis, Biological and Drug‐Likeness Evaluation

Arnold R. Romero Bohórquez, S. C. Mendez-Sanchez, A. Yépes, 2023, ChemistrySelect.

Promising Hybrids Derived from S-Allylcysteine and NSAIDs Fragments against Colorectal Cancer: Synthesis, In-vitro Evaluation, Drug-Likeness and In-silico ADME/tox Studies

Angie Herrera-R, Wilson Castrillón, A. Yépes, 2021, Iranian Journal of Pharmaceutical Research : IJPR.

A Biologically Active Chromone from Bomarea setacea ( alstroemeriaceae ): Leishmanicidal, Antioxidant and Multilevel Computational Studies

S. Robledo, B. Rojano, Andrés F. Yepes, 2022, ChemistrySelect.

2-Amino-6-methoxy-4-(4-methylanilino)-5-nitrosopyrimidine and ethyl N-[4-(adamantan-1-ylamino)-2-amino-5-nitrosopyrimidin-6-yl]-3-aminopropionate: polarized electronic structures and hydrogen-bonded supramolecular assembly in one and two dimensions.

C. Glidewell, J. Cobo, A. Palma, 2012, Acta crystallographica. Section C, Crystal structure communications.

Biologically Active Quinoline‐Hydrazone Conjugates as Potential Trypanosoma cruzi DHFR‐TS Inhibitors: Docking, Molecular Dynamics, MM/PBSA and Drug‐Likeness Studies

Jorge Quintero-Saumeth, Wilson Cardona-Galeano, Wilson Cardona‐Galeano, 2021 .

Chalcone‐Quinoline Conjugates as Potential T. cruzi Cruzipain Inhibitors: Docking Studies, Molecular Dynamics and Evaluation of Drug‐Likeness

Jorge Quintero-Saumeth, A. Yépes, Wilson Cardona-G, 2020 .

A hydrogen-bonded tetramer in (2RS,4SR)-7-bromo-2-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-naphtho[1,2-b]azepin-4-ol and a three-dimensional hydrogen-bonded framework in (2RS,4SR)-2-(3-methylthiophen-2-yl)-2,3,4,5-tetrahydro-1H-naphtho[1,2-b]azepin-4-ol.

C. Glidewell, J. Cobo, A. Palma, 2013, Acta crystallographica. Section C, Crystal structure communications.

Three closely related thienyl-substituted 1,4-epoxynaphtho[1,2-b]azepines: hydrogen-bonded assembly in one, two and three dimensions.

C. Glidewell, J. Cobo, A. Palma, 2013, Acta crystallographica. Section C, Crystal structure communications.

C. Glidewell, J. Cobo, Lina M. Acosta, 2013, Acta crystallographica. Section C, Crystal structure communications.

Crystal Structure of 2-Exo-Phenyl-2,3,4,5-Tetrahydro-1,4-Epoxinafto[1,2-b]azepine

A. Bahsas, G. Delgado, A. J. Mora, 2012, Journal of Chemical Crystallography.

(2RS,4SR)-7-bromo-2-exo-(2-chlorophenyl)-2,3,4,5-tetrahydro-1,4-epoxynaphtho[1,2-b]azepine: sheets built by the π-stacking of hydrogen-bonded chains.

C. Glidewell, J. Cobo, A. Palma, 2012, Acta crystallographica. Section C, Crystal structure communications.