Katsuki Yokoo

Discovery of a Tricyclic β-Lactam as a Potent Antimicrobial Agent against Carbapenem-Resistant Enterobacterales, Including Strains with Reduced Membrane Permeability and Four-Amino Acid Insertion into Penicillin-Binding Protein 3: Structure-Activity-Relationships and In Vitro and In Vivo Activities.

Rio Nakamura, S. Matsumoto, Toshiaki Aoki, 2022, ACS infectious diseases.

Introduction of a Thio Functional Group to Diazabicyclooctane: An Effective Modification to Potentiate the Activity of β-Lactams against Gram-Negative Bacteria Producing Class A, C, and D Serine β-Lactamases.

Naoki Kohira, Toshiaki Aoki, K. Yamawaki, 2020, ACS infectious diseases.

Synthesis of 2-Thio Substituted 1,6-Diazabicyclo[3.2.1]octane Derivatives, Potent β-Lactamase Inhibitors.

Toshiaki Aoki, K. Yamawaki, Hiroki Kusano, 2020, The Journal of organic chemistry.

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship.

H. Yoshizawa, H. Sugimoto, Rio Nakamura, 2018, European journal of medicinal chemistry.

S-3578, a new broad spectrum parenteral cephalosporin exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Synthesis and structure-activity relationships.

T. Iwaki, H. Yoshizawa, T. Irie, 2002, The Journal of antibiotics.

Novel broad-spectrum and long-acting parenteral cephalosporins having an acyl cyanamide moiety at the C-3 terminal: Synthesis and structure-activity relationships.

S. Yonezawa, Rio Nakamura, M. Tsuji, 2016, European journal of medicinal chemistry.

A novel tricyclic β-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships.

S. Matsumoto, Toshiaki Aoki, K. Yamawaki, 2021, Bioorganic & medicinal chemistry.