I. Ullah

发表

In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

P. Uchil, P. Bjorkman, W. Mothes, 2020, bioRxiv.

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

D. Vézina, E. Haddad, P. Uchil, 2022, iScience.

Molecular basis for antiviral activity of pediatric neutralizing antibodies targeting SARS-CoV-2 Spike receptor binding domain

D. Vézina, E. Haddad, P. Uchil, 2022, bioRxiv.

Trileucine residues in a ligand-CPP-based siRNA delivery platform improve endosomal escape of siRNA

Jongkil Kim, Nahyun M. Kim, Priti Kumar, 2017, Journal of drug targeting.

Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.

W. L. Jorgensen, K. Anderson, W. Saltzman, 2019, Antiviral research.

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, Immunity.

Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia

Minhyung Lee, Priti Kumar, Sang-Kyung Lee, 2018, Scientific Reports.

Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir.

J. Sodroski, D. Kaufmann, B. Hahn, 2021, Cell host & microbe.

Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice

Jongkil Kim, Nahyeon Kim, Priti Kumar, 2016, Molecular therapy. Nucleic acids.

A Positioning Device for the Placement of Mice During Intranasal siRNA Delivery to the Central Nervous System.

Priti Kumar, Sang-Kyung Lee, Irfan Ullah, 2019, Journal of visualized experiments : JoVE.

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, Cell Reports.

Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances

N. Zhang, K. Hu, Zhi-Gang Sun, 2022, Frontiers in Oncology.

OP 6.2 – 00195 Targeted genome engineering of human t cells in vivo for HIV cure

P. Uchil, P. Kumar, I. Ullah, 2022, Journal of virus eradication.

SARS-CoV-2 vaccine-associated-tinnitus: A review

Z. Yousaf, Abdul Waris, Summaiyya Waseem, 2022, Annals of Medicine and Surgery.

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, bioRxiv.

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, bioRxiv.

Targeted delivery of recombinant heat shock protein 27 to cardiomyocytes promotes recovery from myocardial infarction.

Nahyeon Kim, Priti Kumar, Sang-Kyung Lee, 2020, Molecular pharmaceutics.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2022, Science advances.

The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

P. Uchil, W. Mothes, A. Finzi, 2022, bioRxiv.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2021, bioRxiv.

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

D. Vézina, L. Stamatatos, P. Uchil, 2022, Cell Reports.

Triple-negative breast cancer: epidemiology, molecular mechanisms, and modern vaccine-based treatment strategies.

Yeong-Geun Lee, Tanveer Ali, Asad Mustafa Karim, 2023, Biochemical pharmacology.

Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia

Minhyung Lee, Priti Kumar, Sang-Kyung Lee, 2018, Scientific Reports.

Nose-to-Brain Delivery of Cancer-Targeting Paclitaxel-loaded Nanoparticles Potentiates Anti-Tumor Effects in Malignant Glioblastoma.

C. Yun, C. Kim, Sun Hwa Kim, 2020, Molecular pharmaceutics.

Intranasal delivery of cancer-targeting doxorubicin-loaded PLGA nanoparticles arrests glioblastoma growth

Sun Hwa Kim, Priti Kumar, Sang-Kyung Lee, 2019, Journal of drug targeting.

Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus.

P. Uchil, E. Fikrig, Priti Kumar, 2018, Cell host & microbe.

Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice

P. Uchil, G. Gendron-Lepage, W. Mothes, 2023, bioRxiv.

VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry

D. Vézina, P. Uchil, C. Baron, 2022, iScience.

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

D. Vézina, L. Stamatatos, P. Uchil, 2021, bioRxiv.

Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models

P. Uchil, E. Fikrig, W. Mothes, 2023, Vaccines.

Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine

M. Bolognesi, P. Uchil, G. Grandi, 2021, bioRxiv.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2022, Science advances.

Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens

P. Uchil, G. Gendron-Lepage, W. Mothes, 2024, iScience.

Proof-of-concept studies with a computationally designed Mpro inhibitor as a synergistic combination regimen alternative to Paxlovid

P. Uchil, W. Mothes, K. Spasov, 2024, Proceedings of the National Academy of Sciences of the United States of America.