James D. Griffin

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The Noncatalytic Domain of Protein-tyrosine Phosphatase-PEST Targets Paxillin for Dephosphorylation in Vivo *

M. Schaller, A. Veillette, Patrick D. Lyons, 2000, The Journal of Biological Chemistry.

Thrombopoietin induces activation of the phosphatidylinositol‐3′ kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL

R. Salgia, M. Sattler, J. Griffin, 1997, Journal of cellular physiology.

The Bovine Papillomavirus E6 Protein Binds to the LD Motif Repeats of Paxillin and Blocks Its Interaction with Vinculin and the Focal Adhesion Kinase*

R. Salgia, P. Howley, Jian-Liang Li, 1997, The Journal of Biological Chemistry.

Molecular Cloning and Characterization of Human Trabeculin-α, a Giant Protein Defining a New Family of Actin-binding Proteins*

D. Auclair, S. Kraeft, Jinyang Zhang, 1999, The Journal of Biological Chemistry.

The Role of Focal Adhesion Kinase Binding in the Regulation of Tyrosine Phosphorylation of Paxillin*

J. M. Broome, R. Salgia, M. Schaller, 1999, The Journal of Biological Chemistry.

The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.

R. Salgia, G. Xu, M. Sattler, 1996, Oncogene.

Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.

S. Lo, R. Salgia, L. Chen, 1995, Oncogene.

BCR/ABL induces multiple abnormalities of cytoskeletal function.

W. Pear, R. Salgia, M. Sattler, 1997, The Journal of clinical investigation.

Hematopoietic growth factors signal through the formation of reactive oxygen species.

R. Salgia, S. Verma, M. Sattler, 1999, Blood.

NOTCH1-induced T-cell leukemia in transgenic zebrafish

A. Look, J. Aster, J. Griffin, 2007, Leukemia.

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

F. Luscinskas, J. Griffin, M. Gimbrone, 1991, Journal of immunology.

Expression of normal monocyte-macrophage differentiation antigens on HL60 promyelocytes undergoing differentiation induced by leukocyte-conditioned medium or phorbol diester.

J. Ritz, J. Griffin, L. Nadler, 1981, Leukemia research.

Bcr/Abl activates transcription of the Bcl-X gene through STAT5.

J. Griffin, F. Gesbert, James D. Griffin, 2000, Blood.

Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.

R. Salgia, M. Hallek, B. Druker, 1994, The Journal of biological chemistry.

Regulation of G1/S transition by cyclins D2 and D3 in hematopoietic cells.

F. Ajchenbaum‐Cymbalista, J. Griffin, K. Ando, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils.

J. Griffin, Liangji Zhou, T. Ernst, 1990, The Journal of biological chemistry.

Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitors

N. Gray, Qingsong Liu, W. Hur, 2012, Leukemia.

The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.

G. Daley, R. Salgia, U. V. von Andrian, 1999, Blood.

Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.

R. Salgia, B. Druker, J. Griffin, 1994, Experimental hematology.

Signal transduction of interleukin-6 involves tyrosine phosphorylation of multiple cytosolic proteins and activation of Src-family kinases Fyn, Hck, and Lyn in multiple myeloma cell lines.

M. Hallek, B. Druker, J. Griffin, 1997, Experimental hematology.

An enzyme-linked immunosorbent assay (ELISA) for the detection of monoclonal antibodies to cell surface antigens on viable cells.

H. Lazarus, J. Griffin, M. Posner, 1982, Journal of immunological methods.

Molecular Cloning Of Human Paxillin, a Focal Adhesion Protein Phosphorylated by P210BCR/ABL(*)

S. Lo, R. Salgia, M. Hallek, 1995, The Journal of Biological Chemistry.

Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.

R. Salgia, B. Druker, J. Griffin, 1993, Experimental hematology.

Regulation of the production and function of granulocytes and monocytes.

S. Cannistra, J. Griffin, James D. Griffin, 1988, Seminars in hematology.

Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase.

M. Hallek, B. Druker, J. Griffin, 1992, Blood.

Differentiation-associated expression of two functionally distinct classes of granulocyte-macrophage colony-stimulating factor receptors by human myeloid cells.

S. Cannistra, J. Griffin, M. Koenigsmann, 1990, The Journal of biological chemistry.

Internalization of the granulocyte-macrophage colony-stimulating factor receptor is not required for induction of protein tyrosine phosphorylation in human myeloid cells.

B. Druker, J. Griffin, K. Okuda, 1991, Blood.

The biology of signal transduction inhibition: basic science to novel therapies.

J. Griffin, James D. Griffin, 2001, Seminars in oncology.

Granulocyte-macrophage colony-stimulating factor induces the expression of the CD11b surface adhesion molecule on human granulocytes in vivo.

M. Socinski, S. Cannistra, J. Griffin, 1988, Blood.

The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.

M. Tomasson, S. Constantinescu, J. Griffin, 2008, Blood.

Identification of functionally distinct domains of human granulocyte-macrophage colony-stimulating factor using monoclonal antibodies.

S. Cannistra, J. Griffin, K. Kaushansky, 1991, Blood.

Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.

M. Belvin, J. Griffin, Y. Kanakura, 1990, Journal of immunology.

Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750.

J. Griffin, D. Frank, R. Inhorn, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML

N. Gray, Xianming Deng, H. Choi, 2010, Leukemia.

Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors.

E. Vellenga, S. Cannistra, J. Griffin, 1987, Blood.