Wolfram Tempel

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RabGAP domain of human TBC1D22B

Yufeng Tong, Wolfram Tempel, C. H. Arrowsmith, 2018 .

The high-throughput protein-to-structure pipeline at SECSG.

Hua Yang, Weihong Zhou, Doowon Lee, 2005, Acta crystallographica. Section D, Biological crystallography.

A test of enhancing model accuracy in high-throughput crystallography

Shuren Wang, Weihong Zhou, David C. Richardson, 2005, Journal of Structural and Functional Genomics.

WWE domain of human HUWE1

Yufeng Tong, Wolfram Tempel, C. H. Arrowsmith, 2018 .

Human METTL3-METTL14 complex

Cheryl H. Arrowsmith, Wolfram Tempel, C. Bountra, 2016 .

Table 1, Extended probe submitted to the MLSMR

Douglas S. Auld, Henrike Veith, Hee-Won Park, 2013 .

human SETD8 in complex with MS2177

Anqi Ma, Jian Jin, Nicolas Babault, 2016 .

PWWP1 domain of NSD2 in complex with MR837

Yanli Liu, Cheryl H. Arrowsmith, Wolfram Tempel, 2019 .

High throughput crystallography at SGC Toronto: an overview.

Wolfram Tempel, Alexey Bochkarev, A. Bochkarev, 2008, Methods in molecular biology.

Parameter-space screening: a powerful tool for high-throughput crystal structure determination.

Dawei Lin, Jeremy L. Praissman, Wolfram Tempel, 2005, Acta crystallographica. Section D, Biological crystallography.

The First Agmatine/Cadaverine Aminopropyl Transferase: Biochemical and Structural Characterization of an Enzyme Involved in Polyamine Biosynthesis in the Hyperthermophilic Archaeon Pyrococcus furiosus

Francis E. Jenney, Michael W. W. Adams, Wolfram Tempel, 2007, Journal of Bacteriology.

Life in the fast lane for protein crystallization and X-ray crystallography.

Jeremy L. Praissman, Wolfram Tempel, Zhi-Jie Liu, 2005, Progress in biophysics and molecular biology.

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.

Alexey Bochkarev, Wolfram Tempel, Anne Mulichak, 2007, Molecular and biochemical parasitology.

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.

Feng Liu, Sun-Chong Wang, Jian Jin, 2011, Nature chemical biology.

The dynamic conformational landscape of the protein methyltransferase SETD8

Cheng Luo, Jian Jin, Yujun George Zheng, 2019, eLife.

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Matthieu Schapira, James E. Bradner, John R. Engen, 2012, Nature Communications.

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N6-Methyladenosine RNA Demethylation*

Wolfram Tempel, Chao Xu, Christopher J Schofield, 2014, The Journal of Biological Chemistry.

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

X. Shirley Liu, Gert Jan C. Veenstra, Wolfram Tempel, 2012, Cell.

Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

Rafael Najmanovich, Alexey Bochkarev, Abdellah Allali-Hassani, 2007, PLoS biology.

Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

Janet M. Thornton, Abdellah Allali-Hassani, Alexander N. Plotnikov, 2007, PLoS Biology.

The Dynamic Conformational Landscapes of the Protein Methyltransferase SETD8

Cheng Luo, Jian Jin, Hualiang Jiang, 2018, bioRxiv.

The xenograft antigen bound to Griffonia simplicifolia lectin 1-B(4). X-ray crystal structure of the complex and molecular dynamics characterization of the binding site.

Sarah M. Tschampel, Robert J Woods, Wolfram Tempel, 2002, The Journal of biological chemistry.

Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.

Matthieu Schapira, Wenyu Yu, Wolfram Tempel, 2013, Bioorganic & medicinal chemistry.

Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain*

Matthias Buck, Wolfram Tempel, Hee-Won Park, 2007, Journal of Biological Chemistry.

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

Nancy Cheng, Su Qin, Bradley M Dickson, 2015, Nature chemical biology.

Mechanism of Class 1 (Glycosylhydrolase Family 47) α-Mannosidases Involved in N-Glycan Processing and Endoplasmic Reticulum Quality Control*

Wolfram Tempel, Zhi-Jie Liu, Bi-Cheng Wang, 2005, Journal of Biological Chemistry.

Divalent cation tolerant protein CUTA from Homo sapiens O60888

David C. Richardson, Wolfram Tempel, Zhi-Jie Liu, 2004 .

Structural Basis of Substrate-binding Specificity of Human Arylamine N-Acetyltransferases*

Ludmila Dombrovsky, Wolfram Tempel, Peter Loppnau, 2007, Journal of Biological Chemistry.

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain.

Ke Liu, Wolfram Tempel, Chao Xu, 2014, Nature chemical biology.

Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD+

Charles Brenner, Wolfram Tempel, Hee-Won Park, 2007, PLoS biology.

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop.

Haruki Nakamura, Evan Bolton, Zukang Feng, 2016, Structure.