Emily A. Chapman

High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms

Kyle A. Brown, Yutong Jin, Ying Ge, 2023, bioRxiv.

Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics.

Ying Ge, Jake A. Melby, Timothy J. Aballo, 2023, Journal of proteome research.

Integrated Proteomics Identifies Troponin I Isoform Switch as a Regulator of a Sarcomere-Metabolism Axis During Cardiac Regeneration

Wyatt G. Paltzer, Timothy J. Aballo, Rebecca J Salamon, 2023, bioRxiv.

Native Top-Down Mass Spectrometry for Characterizing Sarcomeric Proteins Directly from Cardiac Tissue Lysate.

David S. Roberts, Brad H. Li, Kevin M. Buck, 2024, Journal of the American Society for Mass Spectrometry.

Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics

Ying Ge, David S. Roberts, Jake A. Melby, 2023, Nature communications.

Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics

A. Alpert, Ying Ge, David S. Roberts, 2023, bioRxiv.

Online Mixed-Bed Ion Exchange Chromatography for Native Top-Down Proteomics of Complex Mixtures.

Eli J. Larson, Emily A. Chapman, Zhan Gao, 2024, Journal of proteome research.

Top-down proteomics of myosin light chain isoforms define chamber-specific expression in the human heart.

Sean P. Palecek, T. Kamp, Ying Ge, 2023, Journal of molecular and cellular cardiology.