Vipin Suri

发表

Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases

Xinyi Huang, Xin Xu, Shannon L. Stahler, 2011, The Journal of Biological Chemistry.

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

Zhong Zhong, T. Riera, S. Sweitzer, 2012, PloS one.

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

J. McKew, T. Mansour, J. Xiang, 2007 .

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

J. Xiang, M. Tam, J. Tobin, 2005 .

Serine Metabolism Supports Macrophage IL-1β Production.

J. Rabinowitz, S. Weinberg, N. Chandel, 2019, Cell metabolism.

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

O. Sansom, K. Vousden, R. Ludwig, 2021, Nature Communications.

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.

M. Mann, D. Sabatini, R. Jain, 2020, Cancer discovery.

Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis

M. Mann, D. Sabatini, R. Jain, 2020, bioRxiv.

Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma

J. Rabinowitz, Zemer Gitai, J. Ghergurovich, 2017, Proceedings of the National Academy of Sciences.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Takla Griss, E. Ma, Russell G. Jones, 2017, Cell metabolism.

H6PDH interacts directly with 11beta-HSD1: implications for determining the directionality of glucocorticoid catalysis.

R. Kriz, M. Stahl, W. Stochaj, 2009, Archives of biochemistry and biophysics.

Molecular activation of PPARγ by angiotensin II type 1-receptor antagonists

S. Kirincich, Yan-ling Zhang, D. Erbe, 2006 .

CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless

Jeffrey C. Hall, Vipin Suri, M. Rosbash, 1998, Cell.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Takla Griss, E. Ma, Russell G. Jones, 2017, Cell metabolism.

Sirtuin 1 activator SRT2104 protects Huntington's disease mice

S. Mori, Jiangyang Zhang, V. Suri, 2014, Annals of clinical and translational neurology.

SIRT1 activator SRT3025 provides atheroprotection in ApoE/ mice by increasing hepatic LDL receptor

J. Auwerx, D. Sinclair, T. Lüscher, 2019 .

The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

J. Auwerx, D. Sinclair, T. Lüscher, 2014, European heart journal.

PHARMACOLOGICAL SIRT1 ACTIVATION IMPROVES MORTALITY AND MARKEDLY ALTERS TRANSCRIPTIONAL PROFILES THAT ACCOMPANY EXPERIMENTAL SEPSIS

S. Opal, J. Freudenberg, J. Palardy, 2015, Shock.

Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.

S. Kirincich, Yan-ling Zhang, D. Erbe, 2006, Vascular pharmacology.

Evidence that the TIM Light Response Is Relevant to Light-Induced Phase Shifts in Drosophila melanogaster

Jeffrey C. Hall, M. Rosbash, Zuwei Qian, 1998, Neuron.

Two Novel doubletime Mutants Alter Circadian Properties and Eliminate the Delay between RNA and Protein inDrosophila

M. Rosbash, J. C. Hall, Vipin Suri, 2000, The Journal of Neuroscience.

TIMELESS‐dependent positive and negative autoregulation in the Drosophila circadian clock

M. Rosbash, A. Lanjuin, Vipin Suri, 1999, The EMBO journal.

Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.

K. Svenson, J. Bard, T. Mansour, 2009, Journal of medicinal chemistry.

Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes.

K. Svenson, J. Bard, T. Mansour, 2013, ACS medicinal chemistry letters.

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

J. McKew, T. Mansour, J. Xiang, 2008, Journal of medicinal chemistry.

beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action.

J. McKew, T. Mansour, J. Xiang, 2007, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.

J. Xiang, M. Tam, J. Tobin, 2005, Bioorganic & Medicinal Chemistry Letters.

Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.

J. Xiang, E. Saiah, Zhao‐Kui Wan, 2011, Drug Metabolism Letters.

Engineering CD70-Directed CAR-NK Cells for the Treatment of Hematological and Solid Malignancies

Walker S. Lahr, Beau R. Webber, L. Swiech, 2021, Blood.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Takla Griss, E. Ma, Russell G. Jones, 2017, Cell metabolism.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Takla Griss, E. Ma, Russell G. Jones, 2017, Cell metabolism.

Abstract 2904: CAT-179, an allogeneic NK cell product expressing HER2-CAR, IL-15 and TGFβ dominant negative receptor, durably regresses HER2-expressing xenograft tumors in mice

B. Hamza, D. Picarella, Finola E. Moore, 2023, Cancer Research.