Debora Casandra

发表

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum

J. Rayner, T. Otto, Chengqi Wang, 2023, Scientific Reports.

Highly N-Methylated Peptides from the Antarctic Sponge Inflatella coelosphaeroides Are Active against Plasmodium falciparum.

B. Baker, J. Rocca, J. Adams, 2022, Journal of natural products.

Artemisinin-Resistant Plasmodium falciparum Parasites Exhibit Altered Patterns of Development in Infected Erythrocytes

D. Kyle, A. Hott, L. Morton, 2015, Antimicrobial Agents and Chemotherapy.

Fitness of artemisinin-resistant Plasmodium falciparum in vitro.

D. Kyle, M. S. Tucker, A. Hott, 2015, The Journal of antimicrobial chemotherapy.

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis

J. Rayner, T. Otto, Chengqi Wang, 2018, Science.

ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity.

D. Kyle, J. Burrows, Roman Manetsch, 2016, Journal of medicinal chemistry.

Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1H)-Quinolones with Single Dose Cures.

D. Kyle, P. Parvatkar, Roman Manetsch, 2021, Journal of medicinal chemistry.

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite

J. Rayner, T. Otto, Chengqi Wang, 2020, Nature Communications.

A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum

T. Otto, Chengqi Wang, L. Cui, 2023, mSphere.

Synthesis of Mono- and Bisperoxide-Bridged Artemisinin Dimers to Elucidate the Contribution of Dimerization to Antimalarial Activity.

D. Kyle, Roman Manetsch, Victoria C Mendiola, 2021, ACS infectious diseases.

Chemogenomic Profiling of a Plasmodium falciparum Transposon Mutant Library Reveals Shared Effects of Dihydroartemisinin and Bortezomib on Lipid Metabolism and Exported Proteins

J. Rayner, T. Otto, Chengqi Wang, 2023, Microbiology spectrum.

Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies.

D. Kyle, J. Burrows, Raghupathi Neelarapu, 2017, Journal of medicinal chemistry.