Valerie E. Coleburn

Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system.

John A. Robinson, Raymond J. Unwalla, G. Krishnamurthy, 2010, Bioorganic & medicinal chemistry letters.

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate.

Raymond J. Unwalla, P. Bodine, R. Magolda, 2009, Journal of medicinal chemistry.

In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity.

Y. Kharode, F. Bex, B. Bhat, 2004, Bone.

Parathyroid hormone synergizes with non‐cyclic AMP pathways to activate the cyclic AMP response element

R. Bhat, P. Bodine, F. Bex, 2009, Journal of cellular biochemistry.

Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.

R. Bhat, A. Anisowicz, K. Allen, 2007, Gene.