A. Lee

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19 F NMR of monofluorostearic acids in lecithin vesicles.

N. Birdsall, J. Metcalfe, Y. K. Levine, 1971, Biochimica et biophysica acta.

Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum at Glu-439 with 5-(bromomethyl)fluorescein.

M. Gore, A. M. Mata, J. East, 1993, Biochemistry.

Localization of Cys-344 on the (Ca(2+)-Mg(2+)-ATPase of sarcoplasmic reticulum using resonance energy transfer.

M. Gore, A. M. Mata, J. East, 1993, Biochimica et biophysica acta.

Positions of the sites labeled by N-cyclohexyl-N'-(4-dimethylamino-1-naphthyl)carbodiimide on the (Ca2+ + Mg2+)-ATPase.

A. Lee, J. East, F. Munkonge, 1989, Biochimica et biophysica acta.

The position of the ATP binding site on the (Ca2+ + Mg2+)-ATPase.

A. M. Mata, J. East, C. Gutiérrez-Merino, 1987, Biochimica et biophysica acta.

The coordination chemistry of thallium(I)

A. Lee, 1972 .

Artemisinins target the SERCA of Plasmodium falciparum

S. Krishna, S. Ward, P. O’Neill, 2003, Nature.

Reactions of bis(trimethylsilyl)mercury with mercuric compounds

A. Lee, 1969 .

Covalent and non-covalent inhibitors of the phosphate transporter of sarcoplasmic reticulum.

J. East, H. I. Stefanova, A. Lee, 1991, Biochimica et biophysica acta.

Derivatives of phenylthallium(III) I. The preparation and properties of phenylthallium(III) compounds

A. Lee, 1970 .

High resolution proton relaxation studies of lecithins.

N. Birdsall, N J Birdsall, A G Lee, 1972, Biochimica et biophysica acta.

Lipid-protein interactions in biological membranes: a structural perspective.

A. Lee, A G Lee, Anthony G. Lee, 2003, Biochimica et biophysica acta.

Dipalmitoyl-lecithin: assignment of the 1H and 13C nuclear magnetic resonance spectra, and conformational studies

J. Feeney, N. Birdsall, J. Metcalfe, 1972 .

Thallium(I) and (III) arene sulphinates

A. Lee, 1971 .

Reversible lipid titrations of the activity of pure adenosine triphosphatase-lipid complexes.

N. Birdsall, J. Metcalfe, G. B. Warren, 1974, Biochemistry.

Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes.

N. Birdsall, A. Lee, J. Metcalfe, 1974, Biochemistry.

Complete control of the lipid environment of membrane‐bound proteins: Application to a calcium transport system

N. Birdsall, J. Metcalfe, G. B. Warren, 1974, FEBS letters.

Reconstitution of a calcium pump using defined membrane components.

N. Birdsall, A. Lee, J. Metcalfe, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Functional properties of biological membranes: a physical-chemical approach.

A G Lee, A. Lee, 1975, Progress in biophysics and molecular biology.

Thallium derivatives of imidazole, triazole, and related heterocycles

A. Lee, 1971 .

The mass spectra of some dimethylthallium derivatives

A. Lee, 1969 .

13 C nuclear magnetic resonance relaxation measurements of synthetic lecithins and the effect of spin-labeled lipids.

N. Birdsall, J. Metcalfe, Y. K. Levine, 1972, Biochemistry.

13 C and 1 H nuclear magnetic resonance relaxation measurements of the lipids of sarcoplasmic reticulum membranes.

N. Birdsall, J. Robinson, J. Metcalfe, 1972, Biochemistry.

Exchange rates and numbers of annular lipids for the calcium and magnesium ion dependent adenosinetriphosphatase.

D. Melville, J. East, A. Lee, 1985, Biochemistry.

Lipid phase transitions and phase diagrams. I. Lipid phase transitions.

A. Lee, Anthony G. Lee, 1977, Biochimica et biophysica acta.

Binding of hydrophobic drugs to lipid bilayers and to the (Ca2+ + Mg2+)-ATPase.

E. Rooney, A. Lee, 1983, Biochimica et biophysica acta.

Effects of charged drugs on the phase transition temperatures of phospholipid bilayers.

A. Lee, A. Lee, 1978, Biochimica et biophysica acta.

Interactions between anaesthetics and lipid mixtures. Amines.

A. Lee, 1976, Biochimica et biophysica acta.

Solvent relaxation in lipid bilayers with dansyl probes.

S. Meech, C. Stubbs, D. Phillips, 1985, Biochimica et biophysica acta.

Local anesthesia: the interaction between phospholipids and chlorpromazine, propranolol, and practolol.

A. Lee, 1977, Molecular pharmacology.

Lipid phase transitions and phase diagrams. II. Mictures involving lipids.

A G Lee, Anthony G. Lee, A. Lee, 1977, Biochimica et biophysica acta.

Thermostable endogenous inhibitors of cathepsins B and H.

A. Lee, J. Lenney, J. Tolan, 1979, European journal of biochemistry.

The conformation of pyrethroids bound to lipid bilayers.

J. East, F. Michelangeli, A. Lee, 1990, Biochimica et biophysica acta.

Structure of the SR/ER Ca2+-ATPase

A. Lee, 1996 .

Stimulation of the Ca(2+)-ATPase of sarcoplasmic reticulum by disulfiram.

J. East, A. Starling, A. Lee, 1996, The Biochemical journal.

Mechanism of binding of warfarin enantiomers to recombinant domains of human albumin.

A. Lee, M. Gore, J. East, 2003, Archives of biochemistry and biophysics.

Time-resolved emission spectroscopy of 1,3-dimethyl indole in n-butanol

S. Meech, D. Phillips, A. Lee, 1982 .

Time-resolved emission spectroscopy of the dansyl fluorescence probe.

K. Ghiggino, S. Meech, D. O'connor, 1981, Biochemistry.

Interactions of lipids and proteins: Some general principles

A. Lee, 1987, Journal of bioenergetics and biomembranes.

Membrane solubilization by detergent: use of brominated phospholipids to evaluate the detergent-induced changes in Ca2+-ATPase/lipid interaction.

S. Orlowski, J. Møller, A. Lee, 1989, Biochemistry.

13C NMR Spectra of Lecithin Vesicles and Erythrocyte Membranes

J. Feeney, N. Birdsall, P. Partington, 1971, Nature.

Measurement of fast lateral diffusion of lipids in vesicles and in biological membranes by 1 H nuclear magnetic resonance.

N. Birdsall, J. Metcalfe, A. Lee, 1973, Biochemistry.

The interaction of paramagnetic ions and spin labels with lecithin bilayers.

N. Birdsall, A. Lee, J. Robinson, 1973, Biochimica et biophysica acta.

Nuclear Magnetic Relaxation and the Biological Membrane

N. Birdsall, A. Lee, J. Metcalfe, 1974 .

NMR STUDIES OF LIPIDS IN BILAYERS AND MEMBRANES

A. Lee, J. C. Metcalfe, N. J. M. Birdsall, 1973, Annals of the New York Academy of Sciences.

Structural effects on the interaction of sterols with the (Ca2+ + Mg2+)-ATPase.

J. East, F. Michelangeli, A. Lee, 1990, Biochimica et biophysica acta.

Interactions of cholesterol hemisuccinate with phospholipids and (Ca2+-Mg2+)-ATPase.

A. Lee, E. Rooney, A. Simmonds, 1984, Biochemistry.

Annular and non-annular binding sites on the (Ca2+ + Mg2+)-ATPase.

E. Rooney, O. Jones, J. East, 1982, Biochimica et biophysica acta.

Calculation of dipolar nuclear magnetic relaxation times in molecules with multiple internal rotations. II. Theoretical results for anisotropic over‐all motion of the molecule, and comparison with 13C relaxation times in n ‐alkanes and n ‐alkyl bromides

G. Roberts, N. Birdsall, A. Lee, 1974 .

Lipids and their effects on membrane proteins: evidence against a role for fluidity.

A. Lee, Anthony G. Lee, 1991, Progress in lipid research.

What the structure of a calcium pump tells us about its mechanism.

J. East, Anthony G. Lee, A. Lee, 2001, The Biochemical journal.

Fourier transform emission spectroscopy of the jet‐cooled CCN free radical

P. Bernath, N. Oliphant, C. Brazier, 1990 .

Localization of the hinge region of the Ca(2+)-ATPase of sarcoplasmic reticulum using resonance energy transfer.

K. Baker, J. East, Anthony G. Lee, 1994, Biochimica et biophysica acta.

Interactions between anesthetics and lipid mixtures. Normal alcohols.

A. Lee, 1976, Biochemistry.

The pure-rotational Raman spectrum of disilane

W. Jones, K. Shotton, A. Lee, 1973 .

Effects on ATPase activity of monoclonal antibodies raised against (Ca2+ + Mg2+)-ATPase from rabbit skeletal muscle sarcoplasmic reticulum and their correlation with epitope location.

A. M. Mata, J. East, J. Colyer, 1989, The Biochemical journal.

Membrane lipids: It’s only a phase

A. Lee, A. Lee, 2000, Current Biology.

Are essential fatty acids essential for membrane function?

J. East, A. Lee, R. J. Froud, 1986, Progress in lipid research.

Mechanism of inhibition of the (Ca2(+)-Mg2+)-ATPase by nonylphenol.

S. Orlowski, P. Champeil, J. East, 1990, Biochemistry.

Effects of pyrethroids on the activity of a purified (Ca2+-Mg2+)-ATPase

O. Jones, A. Lee, A. Lee, 1986 .

Fluorescence and kinetic studies of the interactions of pyrethroids with the (Ca2(+) + Mg2+)-ATPase.

J. East, F. Michelangeli, A. Lee, 1990, Biochimica et biophysica acta.

Some principles of membrane structure

A. Lee, 1985, Proceedings of the Nutrition Society.

Interaction of fatty acids with the calcium-magnesium ion dependent adenosinetriphosphatase from sarcoplasmic reticulum.

E. Rooney, O. Jones, J. East, 1982, Biochemistry.

Lipid selectivity of the calcium and magnesium ion dependent adenosinetriphosphatase, studied with fluorescence quenching by a brominated phospholipid.

A. Lee, J. East, A. Lee, 1982, Biochemistry.

Interactions between phospholipids and barbiturates.

A. Lee, A. Lee, Anthony G. Lee, 1976, Biochimica et biophysica acta.

The interactions between phosphatidylcholines and anaesthetic steroids.

A. Lee, 1979, Biochemical pharmacology.

Sex differences in the metabolism of ethanol and acetaldehyde in normal subjects.

M. Arthur, R. Wright, A. Lee, 1984, Clinical science.

The potassium channel KcsA and its interaction with the lipid bilayer

J. East, Anthony G. Lee, S. J. Alvis, 2003, Cellular and Molecular Life Sciences CMLS.

An electrophysiological and spectroscopic study of the properties and structure of biological calcium channels. Investigations of a model ion channel.

C. J. Salter, A. Lee, D. Reid, 1992, Biochimica et biophysica acta.

Fluorescence studies of chlorophyll a incorporated into lipid mixtures, and the interpretation of "phase" diagrams.

A. Lee, A. Lee, 1975, Biochimica et biophysica acta.

Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum with 4-(bromomethyl)-6,7-dimethoxycoumarin: detection of conformational changes.

M. Gore, J. East, H. I. Stefanova, 1992, Biochemistry.

Anionic phospholipids decrease the rate of slippage on the Ca(2+)-ATPase of sarcoplasmic reticulum.

J. East, S. Mall, J. Pilot, 1999, The Biochemical journal.

Binding of long-chain alkyl derivatives to lipid bilayers and to (Ca2+-Mg2+)-ATPase.

E. Rooney, J. East, R. J. Froud, 1986, Biochemistry.

How lipids interact with an intrinsic membrane protein: the case of the calcium pump.

Anthony G. Lee, A. Lee, 1998, Biochimica et biophysica acta.

Cardiac Ca2+-ATPase and phospholamban

A. Lee, 1996 .

Interactions of dihydroxybenzenes with the Ca(2+)-ATPase: separate binding sites for dihydroxybenzenes and sesquiterpene lactones.

J. East, M. Wictome, A. Lee, 1995, Biochemistry.

Characterization of Ca2+ uptake and release by vesicles of skeletal-muscle sarcoplasmic reticulum.

G. Gould, A. Lee, J. East, 1987, The Biochemical journal.

Changes in lipid fluidity and fatty acid composition with altered culture temperature in Tetrahymena pyriformis-NT1.

G. A. Kerkut, I. Brown, J. Connolly, 1985, Comparative biochemistry and physiology. A, Comparative physiology.

Temperature-dependent changes in the swimming behaviour of Tetrahymena pyriformis-NT1 and their interrelationships with electrophysiology and the state of membrane lipids.

G. A. Kerkut, I. Brown, J. Connolly, 1985, Comparative biochemistry and physiology. A, Comparative physiology.

The effects of temperature upon the electrophysiological properties of Tetrahymena pyriformis-NT1.

G. A. Kerkut, I. Brown, J. Connolly, 1985, Comparative biochemistry and physiology. A, Comparative physiology.

Membrane fluidity is not an important physiological regulator of the (Ca2+-Mg2+)-dependent ATPase of sarcoplasmic reticulum.

O. Jones, J. East, A. Simmonds, 1984, The Journal of biological chemistry.

Effect of phospholipid:protein ratio on the state of aggregation of the (Ca2+-Mg2+)-ATPase.

E. Rooney, J. East, F. Michelangeli, 1988, Biochemistry.

State of aggregation of the (Ca2+ + Mg2+)-ATPase studied using saturation-transfer electron spin resonance.

J. East, R. Napier, A. Lee, 1987, Biochimica et biophysica acta.

Mechanism of inhibition of the Ca(2+)-ATPase by spermine and other polycationic compounds.

J. East, A. Starling, G. Hughes, 1994, Biochemistry.

Mechanism of stimulation of the calcium adenosinetriphosphatase by jasmone.

J. East, A. Starling, G. Hughes, 1994, Biochemistry.

Effects of phospholipids on the function of (Ca2(+)-Mg2+)-ATPase.

J. East, F. Michelangeli, E. Grimes, 1991, Biochemistry.

Effects of phospholipids on binding of calcium to (Ca2(+)-Mg2(+)-ATPase.

S. Orlowski, P. Champeil, J. East, 1990, Biochemistry.

The organisation of cholesterol and ergosterol in lipid bilayers based on studies using non-perturbing fluorescent sterol probes.

D. Wilton, J. Rogers, A. Lee, 1979, Biochimica et biophysica acta.

A fast passive Ca2+ efflux mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles.

G. Gould, J. East, J. McWHIRTER, 1987, Biochimica et biophysica acta.

Characterisation of a novel Ca2+ pump inhibitor (bis-phenol) and its effects on intracellular Ca2+ mobilization.

G. Brown, J. East, F. Michelangeli, 1994, Biochimica et biophysica acta.

Probing the nucleotide binding site of sarcoplasmic reticulum (Ca2(+)-Mg2)-ATPase with anti-fluorescein antibodies.

A. M. Mata, J. East, A. E. Schofield, 1989, Biochemical Society transactions.

Binding sites for cholesterol on Ca(2+)-ATPase studied by using a cholesterol-containing phospholipid.

J. East, J. Ding, A. Starling, 1994, Biochemistry.

Effects of phosphatidylcholine fatty acyl chain length on calcium binding and other functions of the (Ca(2+)-Mg2+)-ATPase.

A. Lee, J. East, A. Starling, 1993, Biochemistry.

Effects of lipids and long-chain alkyl derivatives on the activity of (Ca2+-Mg2+)-ATPase.

O. Jones, J. East, R. J. Froud, 1986, Biochemistry.

A kinetic model for the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum.

G. Gould, A. Lee, J. East, 1986, The Biochemical journal.

Mechanism of inhibition of the Ca(2+)-ATPase by melittin.

A. Lee, K. Baker, J. East, 1995, Biochemistry.

Binding of Ca2+ to the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum: equilibrium studies.

J. East, I. Henderson, A. Lee, 1994, The Biochemical journal.

Definition of surface-exposed and trans-membranous regions of the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum using anti-peptide antibodies.

A. M. Mata, J. East, R. Tunwell, 1992, The Biochemical journal.

Mechanism of inhibition of the calcium pump of sarcoplasmic reticulum by thapsigargin.

A. Lee, J. East, M. Wictome, 1992, The Biochemical journal.

Effect of pH on the activity of the Ca2+ + Mg2(+)-activated ATPase of sarcoplasmic reticulum.

J. East, F. Michelangeli, J. Colyer, 1990, The Biochemical journal.

Evidence for the cytoplasmic location of the N- and C-terminal segments of sarcoplasmic reticulum (Ca2+-Mg2+)-ATPase.

N. Green, A. M. Mata, J. East, 1989, Biochemical and biophysical research communications.

A model for the phosphorylation of the Ca2+ + Mg2+-activated ATPase by phosphate.

R. J. Froud, A. Lee, 1986, The Biochemical journal.

Effects of lipid-protein interactions on membrane function

A. Lee, 1995 .

Interaction of sterols with phospholipid bilayers and the (Ca2(+)-Mg2+)-ATPase.

J. East, F. Michelangeli, I. Henderson, 1989, Biochemical Society transactions.

Effects of lipid fatty acyl chain structure on the activity of the (Ca2+ + Mg2+)-ATPase.

J. East, C. Earl, R. J. Froud, 1986, Biochimica et biophysica acta.

Conformational transitions in the Ca2+ + Mg2+-activated ATPase and the binding of Ca2+ ions.

R. J. Froud, A. Lee, 1986, The Biochemical journal.

Interactions of hexachlorocyclohexanes with the (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum.

O. Jones, R. J. Froud, A. Lee, 1985, Biochimica et biophysica acta.

Reconstitution experiments provide no evidence for a role for the 53-kDa glycoprotein in coupling Ca2+ transport to ATP hydrolysis by the (Ca(2+)-Mg2+)-ATPase in sarcoplasmic reticulum.

A. Lee, A. Burgess, J. East, 1991, Biochimica et biophysica acta.

Uptake of Ca2+ mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles.

G. Gould, J. East, J. McWHIRTER, 1987, Biochimica et biophysica acta.

A model for the uptake and release of Ca2+ by sarcoplasmic reticulum.

G. Gould, J. East, J. McWHIRTER, 1987, The Biochemical journal.

A kinetic model for Ca2+ efflux mediated by the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum.

G. Gould, J. East, J. McWHIRTER, 1987, The Biochemical journal.

Effects of Mg2+, anions and cations on the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum.

J. East, R. Napier, H. I. Stefanova, 1987, The Biochemical journal.

Silver ions trigger Ca2+ release by interaction with the (Ca2+-Mg2+)-ATPase in reconstituted systems.

G. Gould, J. East, J. Colyer, 1987, The Journal of biological chemistry.

Selectivity in lipid binding to the bacterial outer membrane protein OmpF.

J. East, A. Lee, A. H. O'Keeffe, 2000, Biophysical journal.

Interaction of antihistamines with lipid bilayers.

M. Gore, E. Rooney, A. Lee, 1979, Biochemical pharmacology.

Analysis of the defect structure of gel-phase lipid.

A. Lee, A. Lee, 1977, Biochemistry.

Mapping epitopes on the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum using fusion proteins.

A. M. Mata, J. East, C. O'Connor, 1991, Biochimica et biophysica acta.

Ca2+ -ATPase structure in the E1 and E2 conformations: mechanism, helix-helix and helix-lipid interactions.

A. Lee, 2002, Biochimica et biophysica acta.

Interaction of phosphatidic acid and phosphatidylserine with the Ca2+-ATPase of sarcoplasmic reticulum and the mechanism of inhibition.

J. East, S. Mall, K. A. Dalton, 1998, Biochemical Journal.

Effects of phosphatidylethanolamines on the activity of the Ca(2+)-ATPase of sarcoplasmic reticulum.

A. Lee, J. East, K. A. Dalton, 1996, The Biochemical journal.

Effects of diet on the function of sarcoplasmic reticulum.

G. Gould, J. East, J. McWHIRTER, 1987, The Biochemical journal.

Lipid-protein interactions in the membrane: studies with model peptides.

J. East, S. Mall, R. Sharma, 1998, Faraday discussions.

Myelin: Delivery by raft

A. Lee, A. Lee, 2001, Current Biology.

Lipid interactions with bacterial channels: fluorescence studies.

A. Lee, P. Marius, J. East, 2005, Biochemical Society transactions.

An investigation of the mechanism of inhibition of the Ca(2+)-ATPase by phospholamban.

J. East, A. Starling, G. Hughes, 1996, The Biochemical journal.

Binding of dansyl propranolol to the (Ca2+ + Mg2+)-ATPase.

E. Rooney, O. Jones, J. East, 1983, Biochimica et biophysica acta.

Fitting fluorescence emission spectra of probes bound to biological membranes.

E. Rooney, A. Lee, 1986, Journal of biochemical and biophysical methods.

Effects of Mg2+ and ATP on the phosphate transporter of sarcoplasmic reticulum.

J. East, S. Jane, H. I. Stefanova, 1991, Biochimica et Biophysica Acta.

Effects of phospholipid fatty acyl chain length on phosphorylation and dephosphorylation of the Ca(2+)-ATPase.

A. Lee, J. East, A. Starling, 1995, The Biochemical journal.

Effects of bilayer thickness on the activity of diacylglycerol kinase of Escherichia coli.

A. Lee, J. East, J. Pilot, 2001, Biochemistry.

Hydrophobic mismatch and the incorporation of peptides into lipid bilayers: a possible mechanism for retention in the Golgi.

R J Webb, J. East, A G Lee, 1998, Biochemistry.

Biomembranes : a multi-volume treatise

A. Lee, 1995 .

Localization of endoplasmic reticulum in living cells using green fluorescent protein chimeras.

J. Chad, J. East, P. Adams, 1998, Biochemical Society Transactions.

Self-association of model transmembrane alpha-helices is modulated by lipid structure.

A. Lee, R. Sharma, J. East, 2001, Biochemistry.

Chemical crosslinking and enzyme kinetics provide no evidence for a regulatory role for the 53 kDa glycoprotein of sarcoplasmic reticulum in calcium transport.

A. Lee, A. Burgess, A. M. Mata, 1991, Biochimica et biophysica acta.

Cloning and expression of an insect Ca(2+)-ATPase from Heliothis virescens.

A. Lee, J. East, P. J. Lockyer, 1998, Biochimica et biophysica acta.

13C-enriched phosphatidylethanolamines from Escherichia coli.

N. Birdsall, D. Ellar, J. Metcalfe, 1975, Biochimica et biophysica acta.

Transmembranous organization of (Ca2(+)-Mg2+)-ATPase from sarcoplasmic reticulum. Evidence for lumenal location of residues 877-888.

J. East, I. Matthews, R. Sharma, 1990, The Journal of biological chemistry.

Preparation and properties of tris(trimethylsilyl)thallium

G. Sheldrick, E. Ebsworth, A. Lee, 1969 .

Reactions of trimethylthallium with compounds containing an acidic hydrogen

G. Sheldrick, A. Lee, 1969 .

Effects of pH on phosphorylation of the Ca2+-ATPase of sarcoplasmic reticulum by inorganic phosphate.

J. East, A. Lee, Y. M. Khan, 1997, The Biochemical journal.

Effects of polycations on Ca2+ binding to the Ca(2+)-ATPase.

J. East, G. Hughes, A. Lee, 1995, The Biochemical journal.

Characterization of the single Ca(2+)-binding site on the Ca(2+)-ATPase reconstituted with short- or long-chain phosphatidylcholines.

J. East, A. Starling, A. Lee, 1994, The Biochemical journal.

Interactions of pyrene derivatives with lipid bilayers and with (Ca2+-Mg2+)-ATPase.

O. Jones, A. Lee, 1985, Biochemistry.

The hydrophilic domain of phospholamban inhibits the Ca2+ transport step of the Ca(2+)-ATPase.

A. Lee, J. East, G. Hughes, 1994, The Biochemical journal.