David M. Williams

发表

The synthesis of a tricyclic pyrrolopyrimidine related toN 6-hydroxyadenine

Daniel M. Brown, D. Yakovlev, David M. Williams, 1997 .

Some pyrrolopyrimidine chemistry directed to the synthesis of tricyclic purine analogues

David M Williams, Daniel M. Brown, David M. Williams, 1995 .

Stereoselective synthesis of novel uracil polyoxin C conjugates as substrate analogues of chitin synthase.

A. Plant, P. Thompson, David M. Williams, 2008, The Journal of organic chemistry.

A concise stereoselective synthesis of pterosin B

E. Allen, David M. Williams, Hannah R. Dexter, 2018, Tetrahedron Letters.

Synthesis of Suitably-Protected Phosphoramidites of 2′-Fluoro-2′-Deoxyguanosine and 2′-Amino-2′-Deoxyguanosine for Incorporation Into Oligoribonucleotides

David M Williams, F. Eckstein, F. Benseler, 1992 .

A new and versatile synthesis of 5-substituted pyrrolo[2,3-d]pyrimidines

David M Williams, D. Edmont, David M. Williams, 2000 .

Bis(μ‐diselenido‐μ‐Se,μ‐Se')‐bis[dichlorobis(tetrahydrothiophene)niobium(IV)](Nb–Nb), [Nb2Cl4Se4(C4H8S)4]

M. Drew, D. A. Rice, David M. Williams, 1984 .

Studies of niobium selenido-halides: crystal structure of [Nb2Cl4(Se2)2(SMe2)4]

M. Drew, D. A. Rice, David M. Williams, 1984 .

High-co-ordination-number compounds of niobium and tantalum: reactions of niobium and tantalum halides and sulphide-halides with sodium diethyldithiocarbamate. The crystal structures of [Nb(S2CNEt2)4]Br, Nb(S2CNEt2)3S, and Ta(S2CNEt2)3(S2)

M. Drew, D. A. Rice, David M. Williams, 1985 .

Some co-ordination compounds of TaCl3S and TaBr3S. X-Ray crystal structure of [TaCl3S(PhSCH2CH2SPh)]

M. Drew, D. A. Rice, David M. Williams, 1984 .

The reactions of tetrahydrothiophene (tht) with tribromosulphidoniobium(V) and trichlorosulphidoniobium(V) and the crystal structures of three of the products Nb2Cl4S3·4tht, Nb2Br4S3·4tht, and NbBr3S·2tht

M. Drew, David M Williams, D. A. Rice, 1983 .

Synthesis of Nb(O2H5C7)3Y (Y = O, S and Se): Crystal structure of oxo-tris-(tropolonato)niobium(V) monohydrate: a seven coordinate monomer containing a terminal NbO bond

M. Drew, David M Williams, D. A. Rice, 1986 .

Crystal and molecular structure of the tetra-tetrahydrothiophene adduct of Nb2Br4S3: A species containing a single metalmetal bond and a NbμSμ(S2)Nb bridge

M. Drew, D. A. Rice, I. Baba, 1980 .

The crystal structure of disulphido-tris(N,N,-diethyl-dithiocarbamato)tantalum(V): A monomeric and eight co-ordinate species containing a novel tantalum-disulphide moiety

M. Drew, D. A. Rice, David M. Williams, 1984 .

Niobium(IV) sulphidohalides: preparation of Nb2X4S3 and Nb2X4S3·nL [X = Br or Cl; n= 4, L = NCMe, SMe2, or tetrahydrothiophene (tht); n= 2, L = PhSCH2CH2SPh]. Crystal and molecular structure of Nb2Cl4S2·4tht

M. Drew, D. A. Rice, David M. Williams, 1985 .

The synthesis and properties of oligoribonucleotide-spermine conjugates.

J. Grasby, David M Williams, Andrew Marsh, 2004, Organic & biomolecular chemistry.

Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT)

G. Margison, Nicola Glynn, David M Williams, 2006, Nucleic acids research.

Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation

B. F. Taylor, Nicholas H Williams, David M Williams, 2005, Nucleic acids research.

7,8-Dihydropyrido[2,3-d]pyrimidin-2-one; a bicyclic cytosine analogue capable of enhanced stabilisation of DNA duplexes.

N. Buurma, David M Williams, T. Shibata, 2006, Chemical communications.

Insights into the DNA stabilizing contributions of a bicyclic cytosine analogue: crystal structures of DNA duplexes containing 7,8-dihydropyrido [2,3-d]pyrimidin-2-one

M. Sekine, M. Tsunoda, T. Shibata, 2010, Nucleic acids research.

Novel syntheses of (Z)-alkene and alkane base-modified nucleosides.

J. Grasby, S. E. Lee, David M Williams, 2000 .

The syntheses of tricyclic analogues of O6-methylguanine.

David M Williams, David M. Hammond, D. Edmont, 2003, Organic & biomolecular chemistry.

Alkylated DNA damage flipping bridges base and nucleotide excision repair

John A Tainer, Oliver Fleck, J. Tainer, 2009, Nature.

Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O6-methylguanine and their recognition by MGMT and Atl1

Timothy D. Craggs, G. Margison, A. Povey, 2020, Nucleosides, nucleotides & nucleic acids.

Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.

J. Grasby, David M. Williams, A. Sidorov, 2004, Nucleic acids research.

Interstrand disulfide crosslinking of DNA bases supports a double nucleotide unpairing mechanism for flap endonucleases.

L. Finger, J. Grasby, N. Patel, 2012, Chemical communications.

O⁶-carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine.

G. Margison, M. Tsunoda, David M Williams, 2014, Acta crystallographica. Section D, Biological crystallography.

Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations

G. Margison, M. Tsunoda, David M Williams, 2013, Nucleic acids research.

Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links

K. J. Patel, L. Finger, J. Grasby, 2022, Journal of the American Chemical Society.

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

J. Chin, K. J. Patel, Koichi Sato, 2020, Nature.

Novel Syntheses of (Z)‐Alkene and Alkane Based‐Modified Nucleosides.

J. Grasby, S. E. Lee, David M Williams, 2000 .

The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase

G. Margison, A. Povey, C. Eyers, 2013, Nucleic acids research.

Synthesis of Tricyclic Nucleoside Analogue of O6-Methyl-2'-Deoxyguanosine

David M Williams, K. Abdu, David M. Williams, 2013 .

Recognition of base-pairing by DNA polymerases during nucleotide incorporation: the properties of the mutagenic nucleotide dPTP alphaS.

D. Hornby, A. Hamilton, V. Harris, 2003, Organic & biomolecular chemistry.

The effect of tautomeric constant on the specificity of nucleotide incorporation during DNA replication: support for the rare tautomer hypothesis of substitution mutagenesis.

H. Adams, D. Hornby, David M Williams, 2003, Journal of molecular biology.

Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.

J. Tainer, M. Santibanez-Koref, G. Margison, 2012, Molecular cell.

A novel DNA damage recognition protein in Schizosaccharomyces pombe

M. Santibanez-Koref, G. Margison, Ghazala Begum, 2006, Nucleic acids research.

Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends

J. Tainer, L. Finger, J. Exell, 2012, Nucleic acids research.

Bypass of Mutagenic O(6)-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases.

S. Sturla, Michael H Räz, B. van Loon, 2016, Chemical research in toxicology.

The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O6-alkylguanine DNA adducts

A. Marx, S. Sturla, L. A. Wyss, 2016, Nucleic acids research.

Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation–π interactions

C. Hunter, J. Tainer, G. Margison, 2012, Proceedings of the National Academy of Sciences.

Convenient and Efficient Syntheses of Oligodeoxyribonucleotides Containing O 6-(Carboxymethyl)Guanine and O 6-(4-Oxo-4-(3-Pyridyl)Butyl)Guanine

G. Margison, A. Povey, A. Watson, 2012, Nucleosides, nucleotides & nucleic acids.

The Synthesis and Properties of Tricyclic Analogues of S6-Methylthioguanine and O6-Methylguanine

H. Adams, G. Margison, T. Shibata, 2008 .