Yuta Sakamaki

A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.

N. Ito, T. Ikura, Y. Inaba, 2009, Journal of medicinal chemistry.

Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.

N. Ito, T. Ikura, T. Itoh, 2015, Bioorganic & medicinal chemistry.

Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands.

N. Ito, T. Itoh, Y. Inaba, 2012, Journal of medicinal chemistry.

Potent antagonist for the vitamin D receptor: vitamin D analogues with simple side chain structure.

Y. Inaba, Keiko Yamamoto, N. Yoshimoto, 2010, Journal of medicinal chemistry.