Jérémie Prévost

发表

Across functional boundaries: making non-neutralizing antibodies to neutralize HIV-1 and mediate Fc-mediated effector killing of infected cells

D. Vézina, M. Pazgier, W. Tolbert, 2021, bioRxiv.

A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies

F. Kirchhoff, P. Bjorkman, B. Hahn, 2015, Journal of Virology.

Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env

M. Pazgier, W. Tolbert, J. Richard, 2019, Journal of Virology.

Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4+ T Cell

J. Kappes, F. Kirchhoff, B. Hahn, 2021, bioRxiv.

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

D. Vézina, E. Haddad, P. Uchil, 2022, iScience.

Molecular basis for antiviral activity of pediatric neutralizing antibodies targeting SARS-CoV-2 Spike receptor binding domain

D. Vézina, E. Haddad, P. Uchil, 2022, bioRxiv.

HIV-1 Vpu restricts Fc-mediated effector functions in vivo

B. Haynes, S. Zolla-Pazner, D. Burton, 2022, bioRxiv.

Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells

D. Vézina, M. Pazgier, W. Tolbert, 2021, mBio.

SARS-CoV-2 seroprevalence among blood donors in Québec, and analysis of symptoms associated with seropositivity: a nested case-control study

J. Prévost, G. Gendron-Lepage, A. Finzi, 2021, Canadian Journal of Public Health.

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

D. Vézina, V. Martel-Laferrière, D. Kaufmann, 2022, Cell reports.

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site

J. Sodroski, F. Kirchhoff, B. Hahn, 2020, mBio.

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses

D. Vézina, V. Martel-Laferrière, D. Kaufmann, 2021, Cell Host and Microbe.

Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike

Matthew S. Miller, E. Haddad, J. Richard, 2020, bioRxiv.

Impact of HIV-1 Envelope Conformation on ADCC Responses.

Nirmin Alsahafi, J. Richard, Shilei Ding, 2017, Trends in microbiology.

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Kelly A. Fusco, Maria Cristina Lopes, D. Devine, 2021, Nature Medicine.

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, Immunity.

Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality

J. Richards, D. Kaufmann, A. Dyachenko, 2021, medRxiv.

Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike

Matthew S. Miller, E. Haddad, J. Richard, 2020, Cell Reports Medicine.

The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4+ T cells

F. Kirchhoff, S. Haeryfar, J. Dikeakos, 2021, The Journal of biological chemistry.

The great escape? SARS-CoV-2 variants evading neutralizing responses

J. Prévost, A. Finzi, Jérémie Prévost, 2021, Cell Host & Microbe.

Identification of SARS-CoV-2-specific immune alterations in acutely ill patients

D. Kaufmann, J. Cailhier, J. Richard, 2020, medRxiv.

Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron

W. Stanford, J. Dikeakos, J. Prévost, 2022, iScience.

Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and Omicron

W. Stanford, J. Dikeakos, J. Prévost, 2022, bioRxiv.

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

J. Sodroski, Laura L. Sutherland, B. Haynes, 2018, Nature Communications.

Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals

V. Martel-Laferrière, D. Kaufmann, C. Tremblay, 2020, mBio.

CD4- and Time-Dependent Susceptibility of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

S. Lewin, S. Kent, M. Pazgier, 2019, Journal of Virology.

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

Daniel W. Kulp, D. Irvine, R. Wyatt, 2019, Immunity.

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

Daniel W. Kulp, D. Irvine, R. Wyatt, 2018 .

A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses

D. Vézina, L. Stamatatos, V. Martel-Laferrière, 2021, Cell Host & Microbe.

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses

J. Sodroski, B. Haynes, D. Kaufmann, 2017, Journal of Virology.

Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins

B. Korber, E. Sanders-Buell, J. Prévost, 2016, Journal of Virology.

Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected Cells

S. Kent, M. Pazgier, W. Tolbert, 2018, Journal of Virology.

BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

J. Sodroski, D. Kaufmann, F. Kirchhoff, 2017, Journal of Virology.

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

J. Sodroski, D. Kaufmann, C. Tremblay, 2016, EBioMedicine.

Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2

M. Pazgier, C. Abrams, J. Richard, 2021, Journal of Biological Chemistry.

Waning of SARS-CoV-2 RBD antibodies in longitudinal convalescent plasma samples within 4 months after symptom onset

J. Prévost, A. Finzi, P. Bégin, 2020, Blood.

Multitasking to prevent viral haemorrhagic fevers

D. Safronetz, B. Warner, Jérémie Prévost, 2023, Nature Microbiology.

Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir.

J. Sodroski, D. Kaufmann, B. Hahn, 2021, Cell host & microbe.

Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

D. Kaufmann, Nirmin Alsahafi, J. Richard, 2017, Journal of Virology.

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, Cell Reports.

HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals

D. Vézina, B. Hahn, J. Prévost, 2021, bioRxiv.

Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice

S. Zolla-Pazner, Daniel W. Heindel, J. Prévost, 2021, bioRxiv.

Elicitation of Cluster A and Co-Receptor Binding Site Antibodies Are Required to Eliminate HIV-1 Infected Cells

M. Pazgier, J. Prévost, G. Gendron-Lepage, 2020, Microorganisms.

HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells

D. Kaufmann, F. Kirchhoff, J. Dikeakos, 2020, Journal of Virology.

A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity

D. Vézina, J. Sodroski, M. Pazgier, 2019, Journal of Virology.

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses

Brennan S. Dirk, D. Kaufmann, F. Kirchhoff, 2019, mBio.

An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity.

James B. Munro, J. Sodroski, D. Kaufmann, 2019, Cell host & microbe.

Incomplete Downregulation of CD4 Expression Affects HIV-1 Env Conformation and Antibody-Dependent Cellular Cytotoxicity Responses

J. Kappes, J. Richard, J. Prévost, 2018, Journal of Virology.

Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individuals.

D. Kaufmann, B. Hahn, J. Richard, 2018, Virology.

Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses

D. Kaufmann, F. Kirchhoff, B. Hahn, 2018, mBio.

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity

D. Vézina, J. Richard, J. Prévost, 2021, bioRxiv.

Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset

V. Martel-Laferrière, D. Kaufmann, C. Tremblay, 2021, Cell Reports Medicine.

Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset

V. Martel-Laferrière, D. Kaufmann, C. Tremblay, 2021, bioRxiv.

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, bioRxiv.

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

Daniel S. Terry, D. Ho, J. Mascola, 2020, bioRxiv.

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

Daniel S. Terry, D. Ho, J. Mascola, 2020, Cell Host & Microbe.

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, bioRxiv.

Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays

A. Gingras, M. Drebot, Clark S. Phillipson, 2021, Microbiology spectrum.

High‐throughput detection of antibodies targeting the SARS‐CoV‐2 Spike in longitudinal convalescent plasma samples

J. Richard, S. Anand, J. Prévost, 2020, bioRxiv.

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses

D. Vézina, V. Martel-Laferrière, D. Kaufmann, 2021, bioRxiv.

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

D. Vézina, L. Stamatatos, V. Martel-Laferrière, 2021, bioRxiv.

Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells

Michael D. McLean, D. Burton, G. Shaw, 2021, Journal of virology.

Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120.

D. Kaufmann, M. Pazgier, W. Tolbert, 2023, Cell chemical biology.

Evaluation of a Commercial Culture-Free Neutralization Antibody Detection Kit for Severe Acute Respiratory Syndrome-Related Coronavirus-2 and Comparison With an Antireceptor-Binding Domain Enzyme-Linked Immunosorbent Assay

M. Drebot, J. Prévost, G. Gendron-Lepage, 2021, Open forum infectious diseases.

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

D. Vézina, L. Stamatatos, P. Uchil, 2022, Cell Reports.

Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

J. Dikeakos, J. Richard, Shilei Ding, 2020, bioRxiv.

Longitudinal analysis of the humoral response to SARS-CoV-2 spike RBD in convalescent plasma donors

J. Prévost, A. Finzi, P. Bégin, 2020, bioRxiv.

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors

Alon Herschhorn, Christopher Gu, Youdong Mao, 2016, Journal of Virology.

HIV-1 Envelope Glycoprotein Cell Surface Localization Is Associated with Antibody-Induced Internalization

M. Pazgier, J. Richard, S. Anand, 2021, Viruses.

A new flow cytometry assay to measure antibody-dependent cellular cytotoxicity against SARS-CoV-2 Spike-expressing cells

J. Richard, J. Prévost, A. Finzi, 2021, STAR Protocols.

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

D. Vézina, L. Stamatatos, P. Uchil, 2021, bioRxiv.

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

D. Matthies, M. Pazgier, W. Tolbert, 2023, Nature communications.

Interaction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins

M. Pazgier, C. Abrams, S. Anand, 2020, bioRxiv.

Temperature Influences the Interaction between SARS-CoV-2 Spike from Omicron Subvariants and Human ACE2

D. Vézina, M. Pazgier, J. Richard, 2022, Viruses.

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

D. Vézina, V. Martel-Laferrière, D. Kaufmann, 2022, Cell reports.

Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates

S. Matsushita, M. Pazgier, W. Tolbert, 2022, Journal of virology.

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

J. Sodroski, Laura L. Sutherland, B. Haynes, 2018, Nature Communications.

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

M. Pazgier, C. Abrams, J. Richard, 2021, bioRxiv.

SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells

J. Richard, Shilei Ding, S. Anand, 2021, Viruses.

HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes

D. Kaufmann, J. Prévost, A. Finzi, 2017, PloS one.

Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity

F. Kirchhoff, B. Hahn, J. Richard, 2023, mBio.

CD4- and Time-Dependent Susceptibility of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

S. Lewin, S. Kent, M. Pazgier, 2019, Journal of Virology.

CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies

J. Richard, H. Medjahed, A. Finzi, 2024, bioRxiv.

Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia

C. Chartrand-Lefebvre, M. Pazgier, W. Tolbert, 2023, The Journal of infectious diseases.

Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

D. Kaufmann, Nirmin Alsahafi, J. Richard, 2017, Journal of Virology.

A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability

S. Xiang, M. Pazgier, W. Tolbert, 2016, Journal of Virology.