P. Mcsheehy

发表

Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.

J. Griffiths, M. Leach, I. Judson, 1998, British Journal of Cancer.

1,25-Dihydroxyvitamin D3 stimulates rat osteoblastic cells to release a soluble factor that increases osteoclastic bone resorption.

P. McSheehy, T. Chambers, P. Mcsheehy, 1987, The Journal of clinical investigation.

The effect of calcium-regulating hormones and prostaglandins on bone resorption by osteoclasts disaggregated from neonatal rabbit bones.

B. Thomson, P. McSheehy, T. Chambers, 1985, Endocrinology.

Causes and consequences of acidic pH in tumors: a magnetic resonance study.

J. Griffiths, M. Stubbs, P. Mcsheehy, 1999, Advances in enzyme regulation.

Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone.

P. McSheehy, T. Chambers, P. Mcsheehy, 1986, Endocrinology.

Prediction of 5-fluorouracil cytotoxicity towards the Walker carcinosarcoma using peak integrals of fluoronucleotides measured by MRS in vivo.

J. Griffiths, M. Prior, P. Mcsheehy, 1989, British Journal of Cancer.

The effects of calcium regulating hormones on bone resorption by isolated human osteoclastoma cells

P. McSheehy, T. Chambers, K. Fuller, 1985, The Journal of pathology.

Osteoblast-like cells in the presence of parathyroid hormone release soluble factor that stimulates osteoclastic bone resorption.

P. McSheehy, T. Chambers, P. Mcsheehy, 1986, Endocrinology.

Enhanced 5-fluorouracil cytotoxicity and elevated 5-fluoronucleotides in the rat Walker carcinosarcoma following methotrexate pre-treatment: a 19F-MRS study in vivo.

J. Griffiths, M. Prior, P. McSheehy, 1992, British Journal of Cancer.

Detection of differential sensitivity to 5‐fluorouracil in ehrlich ascites tumour cells by 19F NMR spectroscopy

J. Griffiths, R. Maxwell, P. McSheehy, 1991, NMR in biomedicine.

19F MRS studies of fluoropyrimidine chemotherapy. A review

J. Griffiths, P. McSheehy, J. Griffiths, 1989, NMR in biomedicine.

Causes and consequences of tumour acidity and implications for treatment.

J R Griffiths, J. Griffiths, M. Stubbs, 2000, Molecular medicine today.

Studies of the differentiation properties of camptothecin in the human leukaemic cells K562.

M. D’Incalci, E. Erba, M. Gervasoni, 1991, European journal of cancer.

Role of pH in tumor-trapping of the anticancer drug 5-fluorouracil.

J. Griffiths, M. Stubbs, P. Mcsheehy, 2000, Advances in enzyme regulation.

Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo

K. Altmann, T. O'reilly, F. Wenger, 2005, The Prostate.

Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies.

Paul Workman, Martin O Leach, Jamal Zweit, 2006, Journal of the National Cancer Institute.

Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics.

J. Griffiths, M. Leach, I. Judson, 2003, European journal of cancer.

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

M. Mayr, A. Harris, D. Perrett, 2011, BMC Cancer.

Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes

J. Griffiths, D. McIntyre, M. Leach, 1999, NMR in biomedicine.

A pharmacokinetic and pharmacodynamic study in vivo of human HT29 tumours using 19F and 31P magnetic resonance spectroscopy.

J. Griffiths, M. Leach, I. Judson, 1997, European journal of cancer.

Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours

G. Peters, J. Griffiths, M. Leach, 2005, Cancer Chemotherapy and Pharmacology.

Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.

John R Griffiths, Yuen-Li Chung, Simon P Robinson, 2002, Cancer research.

Tumor vascular architecture and function evaluated by non‐invasive susceptibility MRI methods and immunohistochemistry

F. Howe, J. Griffiths, A. Heerschap, 2003, Journal of magnetic resonance imaging : JMRI.

CORMAN-DROSTEN REVIEW REPORT CURATED BY AN INTERNATIONAL CONSORTIUM OF SCIENTISTS IN LIFE SCIENCES (ICSLS)

M. Yeadon, U. Kämmerer, R. Klement, 2020 .

External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results.

K. McKernan, R. Malhotra, M. Yeadon, 2020 .

Applications of 19F‐NMR to Oncology

J. Griffiths, L. Lemaire, P. McSheehy, 2007 .

Magnetic Resonance Spectroscopy of Cancer: Clinical Overview

F. Howe, J. Griffiths, P. Mcsheehy, 2002 .

Carbogen breathing increases 5-fluorouracil uptake and cytotoxicity in hypoxic murine RIF-1 tumors: a magnetic resonance study in vivo.

J. Griffiths, M. Leach, S. Robinson, 1998, Cancer research.

The response to carbogen breathing in experimental tumour models monitored by gradient-recalled echo magnetic resonance imaging.

F. Howe, J. Griffiths, S. Robinson, 1997, British Journal of Cancer.

Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS.

J. Griffiths, S. Robinson, M. Stubbs, 2002, Neoplasia.

In vivo detection of ifosfamide by 31P-MRS in rat tumours: increased uptake and cytotoxicity induced by carbogen breathing in GH3 prolactinomas.

J. Griffiths, C. R. Pinkerton, S. Robinson, 1997, British Journal of Cancer.

Nuclear magnetic resonance spectroscopy of cancer.

J. Griffiths, S. Robinson, S. J. Barton, 1997, The British journal of radiology.

Metabolites of 2'-fluoro-2'-deoxy-D-glucose detected by 19F magnetic resonance spectroscopy in vivo predict response of murine RIF-1 tumors to 5-fluorouracil.

J. Griffiths, M. Leach, I. Judson, 2000, Cancer research.

1 , 25-Dihydroxyvitamin D 3 stimulates rat osteoblastic cells to release a soluble factor that increases osteoclastic bone resorption

P. McSheehy, P. Mcsheehy, 2018 .

Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment.

G. Peters, F. Howe, J. Griffiths, 2001, Acta oncologica.

Pre-treatment energy status of primary rat tumours as the best predictor of response to 5-fluorouracil chemotherapy: a magnetic resonance spectroscopy study in vivo

J. Griffiths, L. Lemaire, P. Mcsheehy, 1998, Cancer Chemotherapy and Pharmacology.